Minimum Information about a Biosynthetic Gene cluster.
Identifieur interne : 002B29 ( Main/Exploration ); précédent : 002B28; suivant : 002B30Minimum Information about a Biosynthetic Gene cluster.
Auteurs : Marnix H. Medema [Allemagne] ; Renzo Kottmann [Allemagne] ; Pelin Yilmaz [Allemagne] ; Matthew Cummings [Royaume-Uni] ; John B. Biggins [États-Unis] ; Kai Blin [Danemark] ; Irene De Bruijn [Pays-Bas] ; Yit Heng Chooi [Australie] ; Jan Claesen [États-Unis] ; R Cameron Coates [États-Unis] ; Pablo Cruz-Morales [Mexique] ; Srikanth Duddela [Allemagne] ; Stephanie Düsterhus [Allemagne] ; Daniel J. Edwards [États-Unis] ; David P. Fewer [Finlande] ; Neha Garg [États-Unis] ; Christoph Geiger [Allemagne] ; Juan Pablo Gomez-Escribano [Royaume-Uni] ; Anja Greule [Allemagne] ; Michalis Hadjithomas [États-Unis] ; Anthony S. Haines [Royaume-Uni] ; Eric J N. Helfrich [Suisse] ; Matthew L. Hillwig [États-Unis] ; Keishi Ishida [Allemagne] ; Adam C. Jones [États-Unis] ; Carla S. Jones [États-Unis] ; Katrin Jungmann [Allemagne] ; Carsten Kegler [Allemagne] ; Hyun Uk Kim [Corée du Sud] ; Peter Kötter [Allemagne] ; Daniel Krug [Allemagne] ; Joleen Masschelein [Belgique] ; Alexey V. Melnik [États-Unis] ; Simone M. Mantovani [États-Unis] ; Emily A. Monroe [États-Unis] ; Marcus Moore [Canada] ; Nathan Moss [États-Unis] ; Hans-Wilhelm Nützmann [Royaume-Uni] ; Guohui Pan [États-Unis] ; Amrita Pati [États-Unis] ; Daniel Petras [Allemagne] ; F Jerry Reen [Irlande (pays)] ; Federico Rosconi [Uruguay] ; Zhe Rui [États-Unis] ; Zhenhua Tian [République populaire de Chine] ; Nicholas J. Tobias [Allemagne] ; Yuta Tsunematsu [Japon] ; Philipp Wiemann [États-Unis] ; Elizabeth Wyckoff [États-Unis] ; Xiaohui Yan [États-Unis] ; Grace Yim [Canada] ; Fengan Yu [États-Unis] ; Yunchang Xie [République populaire de Chine] ; Bertrand Aigle [France] ; Alexander K. Apel [Allemagne] ; Carl J. Balibar [États-Unis] ; Emily P. Balskus [États-Unis] ; Francisco Barona-G Mez [Mexique] ; Andreas Bechthold [Allemagne] ; Helge B. Bode [Allemagne] ; Rainer Borriss [Allemagne] ; Sean F. Brady [États-Unis] ; Axel A. Brakhage [Allemagne] ; Patrick Caffrey [Irlande (pays)] ; Yi-Qiang Cheng [États-Unis] ; Jon Clardy [États-Unis] ; Russell J. Cox [Royaume-Uni] ; René De Mot [Belgique] ; Stefano Donadio [Italie] ; Mohamed S. Donia [États-Unis] ; Wilfred A. Van Der Donk [États-Unis] ; Pieter C. Dorrestein [États-Unis] ; Sean Doyle [Irlande (pays)] ; Arnold J M. Driessen [Pays-Bas] ; Monika Ehling-Schulz [Autriche] ; Karl-Dieter Entian [Allemagne] ; Michael A. Fischbach [États-Unis] ; Lena Gerwick [États-Unis] ; William H. Gerwick [États-Unis] ; Harald Gross [Allemagne] ; Bertolt Gust [Allemagne] ; Christian Hertweck [Allemagne] ; Monica Höfte [Belgique] ; Susan E. Jensen [Canada] ; Jianhua Ju [République populaire de Chine] ; Leonard Katz [États-Unis] ; Leonard Kaysser [Allemagne] ; Jonathan L. Klassen [États-Unis] ; Nancy P. Keller [États-Unis] ; Jan Kormanec ; Oscar P. Kuipers [Pays-Bas] ; Tomohisa Kuzuyama [Japon] ; Nikos C. Kyrpides [Arabie saoudite] ; Hyung-Jin Kwon [Corée du Sud] ; Sylvie Lautru [France] ; Rob Lavigne [Belgique] ; Chia Y. Lee [États-Unis] ; Bai Linquan [République populaire de Chine] ; Xinyu Liu [États-Unis] ; Wen Liu [République populaire de Chine] ; Andriy Luzhetskyy [Allemagne] ; Taifo Mahmud [États-Unis] ; Yvonne Mast [Allemagne] ; Carmen Méndez [Espagne] ; Mikko Mets Ketel [Finlande] ; Jason Micklefield [Royaume-Uni] ; Douglas A. Mitchell [États-Unis] ; Bradley S. Moore [États-Unis] ; Leonilde M. Moreira [Portugal] ; Rolf Müller [Allemagne] ; Brett A. Neilan [Australie] ; Markus Nett [Allemagne] ; Jens Nielsen [Suède] ; Fergal O'Gara [Australie] ; Hideaki Oikawa [Japon] ; Anne Osbourn [Royaume-Uni] ; Marcia S. Osburne [États-Unis] ; Bohdan Ostash [Ukraine] ; Shelley M. Payne [États-Unis] ; Jean-Luc Pernodet [France] ; Miroslav Petricek [République tchèque] ; Jörn Piel [Suisse] ; Olivier Ploux [France] ; Jos M. Raaijmakers [Pays-Bas] ; José A. Salas [Espagne] ; Esther K. Schmitt [Suisse] ; Barry Scott [Nouvelle-Zélande] ; Ryan F. Seipke [Royaume-Uni] ; Ben Shen [États-Unis] ; David H. Sherman [États-Unis] ; Kaarina Sivonen [Finlande] ; Michael J. Smanski [États-Unis] ; Margherita Sosio [Italie] ; Evi Stegmann [Allemagne] ; Roderich D. Süssmuth [Allemagne] ; Kapil Tahlan [Canada] ; Christopher M. Thomas [Royaume-Uni] ; Yi Tang [États-Unis] ; Andrew W. Truman [Royaume-Uni] ; Muriel Viaud [France] ; Jonathan D. Walton [États-Unis] ; Christopher T. Walsh [États-Unis] ; Tilmann Weber [Danemark] ; Gilles P. Van Wezel [Pays-Bas] ; Barrie Wilkinson [Royaume-Uni] ; Joanne M. Willey [États-Unis] ; Wolfgang Wohlleben [Allemagne] ; Gerard D. Wright [Canada] ; Nadine Ziemert [Allemagne] ; Changsheng Zhang [République populaire de Chine] ; Sergey B. Zotchev [Norvège] ; Rainer Breitling [Royaume-Uni] ; Eriko Takano [Royaume-Uni] ; Frank Oliver Glöckner [Allemagne]Source :
- Nature chemical biology [ 1552-4469 ] ; 2015.
Descripteurs français
- KwdFr :
- Alcaloïdes (biosynthèse), Bactéries (génétique), Bactéries (métabolisme), Bases de données génétiques, Biologie informatique (normes), Biosynthèse des protéines, Biosynthèse non ribosomique des peptides, Champignons (génétique), Champignons (métabolisme), Coopération internationale, Famille multigénique, Marqueurs génétiques, Métagénome, Peptides (métabolisme), Plantes (génétique), Plantes (métabolisme), Polycétides (métabolisme), Polyosides (biosynthèse), Terminologie comme sujet, Terpènes (métabolisme).
- MESH :
- biosynthèse : Alcaloïdes, Polyosides.
- génétique : Bactéries, Champignons, Plantes.
- métabolisme : Bactéries, Champignons, Peptides, Plantes, Polycétides, Terpènes.
- normes : Biologie informatique.
- Bases de données génétiques, Biosynthèse des protéines, Biosynthèse non ribosomique des peptides, Coopération internationale, Famille multigénique, Marqueurs génétiques, Métagénome, Terminologie comme sujet.
English descriptors
- KwdEn :
- Alkaloids (biosynthesis), Bacteria (genetics), Bacteria (metabolism), Computational Biology (standards), Databases, Genetic, Fungi (genetics), Fungi (metabolism), Genetic Markers, International Cooperation, Metagenome, Multigene Family, Peptide Biosynthesis, Nucleic Acid-Independent, Peptides (metabolism), Plants (genetics), Plants (metabolism), Polyketides (metabolism), Polysaccharides (biosynthesis), Protein Biosynthesis, Terminology as Topic, Terpenes (metabolism).
- MESH :
- chemical , biosynthesis : Alkaloids, Polysaccharides.
- genetics : Bacteria, Fungi, Plants.
- metabolism : Bacteria, Fungi, Peptides, Plants, Polyketides, Terpenes.
- standards : Computational Biology.
- Databases, Genetic, Genetic Markers, International Cooperation, Metagenome, Multigene Family, Peptide Biosynthesis, Nucleic Acid-Independent, Protein Biosynthesis, Terminology as Topic.
DOI: 10.1038/nchembio.1890
PubMed: 26284661
Affiliations:
- Allemagne, Arabie saoudite, Australie, Autriche, Belgique, Canada, Corée du Sud, Danemark, Espagne, Finlande, France, Irlande (pays), Italie, Japon, Mexique, Norvège, Nouvelle-Zélande, Pays-Bas, Portugal, Royaume-Uni, République populaire de Chine, République tchèque, Suisse, Suède, Ukraine, Uruguay, États-Unis
- Angleterre, Arkansas, Bade-Wurtemberg, Berlin, Bohême centrale, Brême (Land), Californie, Canton de Zurich, Connecticut, District de Darmstadt, District de Fribourg-en-Brisgau, District de Tübingen, Finlande occidentale, Floride, Grand Est, Grand Manchester, Groningue (province), Guangdong, Hesse (Land), Hollande-Méridionale, Illinois, Leinster, Lorraine (région), Massachusetts, Michigan, Midlands de l'Ouest, Minnesota, New Jersey, Ontario, Oregon, Pennsylvanie, Province de Flandre-Orientale, Région de Kantō, Région flamande, Sarre (Land), Texas, Trøndelag, Uusimaa, Vienne (Autriche), Wisconsin, Yorkshire-et-Humber, État de New York, Île-de-France
- Berlin, Birmingham, Brême, Cambridge (Massachusetts), East Lansing, Francfort-sur-le-Main, Fribourg-en-Brisgau, Gand, Groningue, Groningue (ville), Hamilton (Ontario), Helsinki, Jiangmen, Leeds, Leyde, Manchester, Maynooth, Nancy, Orsay, Paris, Pittsburgh, Prague, Princeton (New Jersey), Sarrebruck, Tokyo, Trondheim, Turku, Tübingen, Vandœuvre-lès-Nancy, Vienne (Autriche), Zurich
- Université Harvard, Université Johann Wolfgang Goethe de Francfort-sur-le-Main, Université McMaster, Université Paris-Sud, Université d'Helsinki, Université d'État du Michigan, Université de Birmingham, Université de Gand, Université de Groningue, Université de Leeds, Université de Manchester, Université de Pittsburgh, Université de Princeton, Université de Tokyo, Université de Turku, Université nationale d'Irlande à Maynooth, Université technique de Berlin
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Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Minimum Information about a Biosynthetic Gene cluster.</title><author><name sortKey="Medema, Marnix H" sort="Medema, Marnix H" uniqKey="Medema M" first="Marnix H" last="Medema">Marnix H. Medema</name><affiliation wicri:level="3"><nlm:affiliation>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen</wicri:regionArea><placeName><region type="land" nuts="3">Brême (Land)</region><settlement type="city">Brême</settlement></placeName></affiliation></author><author><name sortKey="Kottmann, Renzo" sort="Kottmann, Renzo" uniqKey="Kottmann R" first="Renzo" last="Kottmann">Renzo Kottmann</name><affiliation wicri:level="3"><nlm:affiliation>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen</wicri:regionArea><placeName><region type="land" nuts="3">Brême (Land)</region><settlement type="city">Brême</settlement></placeName></affiliation></author><author><name sortKey="Yilmaz, Pelin" sort="Yilmaz, Pelin" uniqKey="Yilmaz P" first="Pelin" last="Yilmaz">Pelin Yilmaz</name><affiliation wicri:level="3"><nlm:affiliation>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen</wicri:regionArea><placeName><region type="land" nuts="3">Brême (Land)</region><settlement type="city">Brême</settlement></placeName></affiliation></author><author><name sortKey="Cummings, Matthew" sort="Cummings, Matthew" uniqKey="Cummings M" first="Matthew" last="Cummings">Matthew Cummings</name><affiliation wicri:level="4"><nlm:affiliation>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Biggins, John B" sort="Biggins, John B" uniqKey="Biggins J" first="John B" last="Biggins">John B. Biggins</name><affiliation wicri:level="2"><nlm:affiliation>Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Blin, Kai" sort="Blin, Kai" uniqKey="Blin K" first="Kai" last="Blin">Kai Blin</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm</wicri:regionArea><wicri:noRegion>Hørsholm</wicri:noRegion></affiliation></author><author><name sortKey="De Bruijn, Irene" sort="De Bruijn, Irene" uniqKey="De Bruijn I" first="Irene" last="De Bruijn">Irene De Bruijn</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen</wicri:regionArea><wicri:noRegion>Wageningen</wicri:noRegion></affiliation></author><author><name sortKey="Chooi, Yit Heng" sort="Chooi, Yit Heng" uniqKey="Chooi Y" first="Yit Heng" last="Chooi">Yit Heng Chooi</name><affiliation wicri:level="1"><nlm:affiliation>1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA. [3] School of Chemistry and Biochemistry, University of Western Australia, Perth, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA. [3] School of Chemistry and Biochemistry, University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Claesen, Jan" sort="Claesen, Jan" uniqKey="Claesen J" first="Jan" last="Claesen">Jan Claesen</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Coates, R Cameron" sort="Coates, R Cameron" uniqKey="Coates R" first="R Cameron" last="Coates">R Cameron Coates</name><affiliation wicri:level="2"><nlm:affiliation>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Cruz Morales, Pablo" sort="Cruz Morales, Pablo" uniqKey="Cruz Morales P" first="Pablo" last="Cruz-Morales">Pablo Cruz-Morales</name><affiliation wicri:level="1"><nlm:affiliation>Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato, México.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Mexique</country><wicri:regionArea>Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato</wicri:regionArea><wicri:noRegion>Guanajuato</wicri:noRegion></affiliation></author><author><name sortKey="Duddela, Srikanth" sort="Duddela, Srikanth" uniqKey="Duddela S" first="Srikanth" last="Duddela">Srikanth Duddela</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Dusterhus, Stephanie" sort="Dusterhus, Stephanie" uniqKey="Dusterhus S" first="Stephanie" last="Düsterhus">Stephanie Düsterhus</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Edwards, Daniel J" sort="Edwards, Daniel J" uniqKey="Edwards D" first="Daniel J" last="Edwards">Daniel J. Edwards</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry and Biochemistry, California State University, Chico, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry and Biochemistry, California State University, Chico, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Fewer, David P" sort="Fewer, David P" uniqKey="Fewer D" first="David P" last="Fewer">David P. Fewer</name><affiliation wicri:level="4"><nlm:affiliation>Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Garg, Neha" sort="Garg, Neha" uniqKey="Garg N" first="Neha" last="Garg">Neha Garg</name><affiliation wicri:level="2"><nlm:affiliation>Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Geiger, Christoph" sort="Geiger, Christoph" uniqKey="Geiger C" first="Christoph" last="Geiger">Christoph Geiger</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Gomez Escribano, Juan Pablo" sort="Gomez Escribano, Juan Pablo" uniqKey="Gomez Escribano J" first="Juan Pablo" last="Gomez-Escribano">Juan Pablo Gomez-Escribano</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Greule, Anja" sort="Greule, Anja" uniqKey="Greule A" first="Anja" last="Greule">Anja Greule</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Hadjithomas, Michalis" sort="Hadjithomas, Michalis" uniqKey="Hadjithomas M" first="Michalis" last="Hadjithomas">Michalis Hadjithomas</name><affiliation wicri:level="2"><nlm:affiliation>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Haines, Anthony S" sort="Haines, Anthony S" uniqKey="Haines A" first="Anthony S" last="Haines">Anthony S. Haines</name><affiliation wicri:level="4"><nlm:affiliation>School of Biosciences, University of Birmingham, Birmingham, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Biosciences, University of Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region><settlement type="city">Birmingham</settlement></placeName><orgName type="university">Université de Birmingham</orgName></affiliation></author><author><name sortKey="Helfrich, Eric J N" sort="Helfrich, Eric J N" uniqKey="Helfrich E" first="Eric J N" last="Helfrich">Eric J N. Helfrich</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Hillwig, Matthew L" sort="Hillwig, Matthew L" uniqKey="Hillwig M" first="Matthew L" last="Hillwig">Matthew L. Hillwig</name><affiliation wicri:level="4"><nlm:affiliation>Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Ishida, Keishi" sort="Ishida, Keishi" uniqKey="Ishida K" first="Keishi" last="Ishida">Keishi Ishida</name><affiliation wicri:level="1"><nlm:affiliation>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena</wicri:regionArea><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Jones, Adam C" sort="Jones, Adam C" uniqKey="Jones A" first="Adam C" last="Jones">Adam C. Jones</name><affiliation wicri:level="2"><nlm:affiliation>Gordon and Betty Moore Foundation, Palo Alto, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Gordon and Betty Moore Foundation, Palo Alto, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Jones, Carla S" sort="Jones, Carla S" uniqKey="Jones C" first="Carla S" last="Jones">Carla S. Jones</name><affiliation wicri:level="2"><nlm:affiliation>Sustainable Studies Program, Roosevelt University Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Sustainable Studies Program, Roosevelt University Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Jungmann, Katrin" sort="Jungmann, Katrin" uniqKey="Jungmann K" first="Katrin" last="Jungmann">Katrin Jungmann</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Kegler, Carsten" sort="Kegler, Carsten" uniqKey="Kegler C" first="Carsten" last="Kegler">Carsten Kegler</name><affiliation wicri:level="4"><nlm:affiliation>Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement><settlement type="city">Francfort-sur-le-Main</settlement></placeName><orgName type="university">Université Johann Wolfgang Goethe de Francfort-sur-le-Main</orgName></affiliation></author><author><name sortKey="Kim, Hyun Uk" sort="Kim, Hyun Uk" uniqKey="Kim H" first="Hyun Uk" last="Kim">Hyun Uk Kim</name><affiliation wicri:level="1"><nlm:affiliation>1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] BioInformatics Research Center, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] BioInformatics Research Center, Korea Advanced Institute of Science and Technology, Daejeon</wicri:regionArea><wicri:noRegion>Daejeon</wicri:noRegion></affiliation></author><author><name sortKey="Kotter, Peter" sort="Kotter, Peter" uniqKey="Kotter P" first="Peter" last="Kötter">Peter Kötter</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Krug, Daniel" sort="Krug, Daniel" uniqKey="Krug D" first="Daniel" last="Krug">Daniel Krug</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Masschelein, Joleen" sort="Masschelein, Joleen" uniqKey="Masschelein J" first="Joleen" last="Masschelein">Joleen Masschelein</name><affiliation wicri:level="1"><nlm:affiliation>1] Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium. [2] Laboratory of Food Microbiology, KU Leuven, Heverlee, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>1] Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium. [2] Laboratory of Food Microbiology, KU Leuven, Heverlee</wicri:regionArea><wicri:noRegion>Heverlee</wicri:noRegion></affiliation></author><author><name sortKey="Melnik, Alexey V" sort="Melnik, Alexey V" uniqKey="Melnik A" first="Alexey V" last="Melnik">Alexey V. Melnik</name><affiliation wicri:level="2"><nlm:affiliation>Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Mantovani, Simone M" sort="Mantovani, Simone M" uniqKey="Mantovani S" first="Simone M" last="Mantovani">Simone M. Mantovani</name><affiliation wicri:level="2"><nlm:affiliation>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Monroe, Emily A" sort="Monroe, Emily A" uniqKey="Monroe E" first="Emily A" last="Monroe">Emily A. Monroe</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biology, William Paterson University, Wayne, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, William Paterson University, Wayne, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Moore, Marcus" sort="Moore, Marcus" uniqKey="Moore M" first="Marcus" last="Moore">Marcus Moore</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland</wicri:regionArea><wicri:noRegion>Newfoundland</wicri:noRegion></affiliation></author><author><name sortKey="Moss, Nathan" sort="Moss, Nathan" uniqKey="Moss N" first="Nathan" last="Moss">Nathan Moss</name><affiliation wicri:level="2"><nlm:affiliation>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Nutzmann, Hans Wilhelm" sort="Nutzmann, Hans Wilhelm" uniqKey="Nutzmann H" first="Hans-Wilhelm" last="Nützmann">Hans-Wilhelm Nützmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Pan, Guohui" sort="Pan, Guohui" uniqKey="Pan G" first="Guohui" last="Pan">Guohui Pan</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, The Scripps Research Institute, Jupiter, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Pati, Amrita" sort="Pati, Amrita" uniqKey="Pati A" first="Amrita" last="Pati">Amrita Pati</name><affiliation wicri:level="2"><nlm:affiliation>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Petras, Daniel" sort="Petras, Daniel" uniqKey="Petras D" first="Daniel" last="Petras">Daniel Petras</name><affiliation wicri:level="4"><nlm:affiliation>Institut für Chemie, Technische Universität Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Chemie, Technische Universität Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement><settlement type="city">Berlin</settlement></placeName><orgName type="university">Université technique de Berlin</orgName></affiliation></author><author><name sortKey="Reen, F Jerry" sort="Reen, F Jerry" uniqKey="Reen F" first="F Jerry" last="Reen">F Jerry Reen</name><affiliation wicri:level="1"><nlm:affiliation>BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author><author><name sortKey="Rosconi, Federico" sort="Rosconi, Federico" uniqKey="Rosconi F" first="Federico" last="Rosconi">Federico Rosconi</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Bioquímica y Genómica Microbianas, IBCE, Montevideo, Uruguay.</nlm:affiliation><country xml:lang="fr">Uruguay</country><wicri:regionArea>Departamento de Bioquímica y Genómica Microbianas, IBCE, Montevideo</wicri:regionArea><wicri:noRegion>Montevideo</wicri:noRegion></affiliation></author><author><name sortKey="Rui, Zhe" sort="Rui, Zhe" uniqKey="Rui Z" first="Zhe" last="Rui">Zhe Rui</name><affiliation wicri:level="2"><nlm:affiliation>1] Energy Biosciences Institute, University of California Berkeley, Berkeley, California, USA. [2] Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Energy Biosciences Institute, University of California Berkeley, Berkeley, California, USA. [2] Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Tian, Zhenhua" sort="Tian, Zhenhua" uniqKey="Tian Z" first="Zhenhua" last="Tian">Zhenhua Tian</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Tobias, Nicholas J" sort="Tobias, Nicholas J" uniqKey="Tobias N" first="Nicholas J" last="Tobias">Nicholas J. Tobias</name><affiliation wicri:level="4"><nlm:affiliation>Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement><settlement type="city">Francfort-sur-le-Main</settlement></placeName><orgName type="university">Université Johann Wolfgang Goethe de Francfort-sur-le-Main</orgName></affiliation></author><author><name sortKey="Tsunematsu, Yuta" sort="Tsunematsu, Yuta" uniqKey="Tsunematsu Y" first="Yuta" last="Tsunematsu">Yuta Tsunematsu</name><affiliation wicri:level="1"><nlm:affiliation>1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka</wicri:regionArea><wicri:noRegion>Shizuoka</wicri:noRegion></affiliation></author><author><name sortKey="Wiemann, Philipp" sort="Wiemann, Philipp" uniqKey="Wiemann P" first="Philipp" last="Wiemann">Philipp Wiemann</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Wyckoff, Elizabeth" sort="Wyckoff, Elizabeth" uniqKey="Wyckoff E" first="Elizabeth" last="Wyckoff">Elizabeth Wyckoff</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Yan, Xiaohui" sort="Yan, Xiaohui" uniqKey="Yan X" first="Xiaohui" last="Yan">Xiaohui Yan</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, The Scripps Research Institute, Jupiter, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Yim, Grace" sort="Yim, Grace" uniqKey="Yim G" first="Grace" last="Yim">Grace Yim</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Yu, Fengan" sort="Yu, Fengan" uniqKey="Yu F" first="Fengan" last="Yu">Fengan Yu</name><affiliation wicri:level="2"><nlm:affiliation>1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Xie, Yunchang" sort="Xie, Yunchang" uniqKey="Xie Y" first="Yunchang" last="Xie">Yunchang Xie</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Aigle, Bertrand" sort="Aigle, Bertrand" uniqKey="Aigle B" first="Bertrand" last="Aigle">Bertrand Aigle</name><affiliation wicri:level="3"><nlm:affiliation>Dynamique des Génomes et Adaptation Microbienne, Université de Lorraine and Institut National de la Recherche Agronomique (INRA), Unité Mixte de Recherche (UMR) 1128, Vandœuvre-lès-Nancy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Dynamique des Génomes et Adaptation Microbienne, Université de Lorraine and Institut National de la Recherche Agronomique (INRA), Unité Mixte de Recherche (UMR) 1128, Vandœuvre-lès-Nancy</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Lorraine (région)</region><settlement type="city">Vandœuvre-lès-Nancy</settlement><settlement type="city" wicri:auto="agglo">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Apel, Alexander K" sort="Apel, Alexander K" uniqKey="Apel A" first="Alexander K" last="Apel">Alexander K. Apel</name><affiliation wicri:level="3"><nlm:affiliation>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Balibar, Carl J" sort="Balibar, Carl J" uniqKey="Balibar C" first="Carl J" last="Balibar">Carl J. Balibar</name><affiliation wicri:level="2"><nlm:affiliation>Infectious Disease Research, Merck Research Laboratories, Kenilworth, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Infectious Disease Research, Merck Research Laboratories, Kenilworth, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Balskus, Emily P" sort="Balskus, Emily P" uniqKey="Balskus E" first="Emily P" last="Balskus">Emily P. Balskus</name><affiliation wicri:level="4"><nlm:affiliation>Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region><settlement type="city">Cambridge (Massachusetts)</settlement></placeName><orgName type="university">Université Harvard</orgName></affiliation></author><author><name sortKey="Barona G Mez, Francisco" sort="Barona G Mez, Francisco" uniqKey="Barona G Mez F" first="Francisco" last="Barona-G Mez">Francisco Barona-G Mez</name><affiliation wicri:level="1"><nlm:affiliation>Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato, México.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Mexique</country><wicri:regionArea>Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato</wicri:regionArea><wicri:noRegion>Guanajuato</wicri:noRegion></affiliation></author><author><name sortKey="Bechthold, Andreas" sort="Bechthold, Andreas" uniqKey="Bechthold A" first="Andreas" last="Bechthold">Andreas Bechthold</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Bode, Helge B" sort="Bode, Helge B" uniqKey="Bode H" first="Helge B" last="Bode">Helge B. Bode</name><affiliation wicri:level="4"><nlm:affiliation>1] Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany. [2] Buchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt, Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany. [2] Buchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt, Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement><settlement type="city">Francfort-sur-le-Main</settlement></placeName><orgName type="university">Université Johann Wolfgang Goethe de Francfort-sur-le-Main</orgName></affiliation></author><author><name sortKey="Borriss, Rainer" sort="Borriss, Rainer" uniqKey="Borriss R" first="Rainer" last="Borriss">Rainer Borriss</name><affiliation wicri:level="3"><nlm:affiliation>Fachbereich Phytomedizin, Albrecht Thaer Institut, Humboldt Universität Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Fachbereich Phytomedizin, Albrecht Thaer Institut, Humboldt Universität Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Brady, Sean F" sort="Brady, Sean F" uniqKey="Brady S" first="Sean F" last="Brady">Sean F. Brady</name><affiliation wicri:level="2"><nlm:affiliation>Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Brakhage, Axel A" sort="Brakhage, Axel A" uniqKey="Brakhage A" first="Axel A" last="Brakhage">Axel A. Brakhage</name><affiliation wicri:level="1"><nlm:affiliation>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena</wicri:regionArea><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Caffrey, Patrick" sort="Caffrey, Patrick" uniqKey="Caffrey P" first="Patrick" last="Caffrey">Patrick Caffrey</name><affiliation wicri:level="1"><nlm:affiliation>UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Yi Qiang" sort="Cheng, Yi Qiang" uniqKey="Cheng Y" first="Yi-Qiang" last="Cheng">Yi-Qiang Cheng</name><affiliation wicri:level="2"><nlm:affiliation>UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Clardy, Jon" sort="Clardy, Jon" uniqKey="Clardy J" first="Jon" last="Clardy">Jon Clardy</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Cox, Russell J" sort="Cox, Russell J" uniqKey="Cox R" first="Russell J" last="Cox">Russell J. Cox</name><affiliation wicri:level="1"><nlm:affiliation>1] Institut für Organische Chemie, Leibniz Universität Hannover, Hannover, Germany. [2] School of Chemistry, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>1] Institut für Organische Chemie, Leibniz Universität Hannover, Hannover, Germany. [2] School of Chemistry, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="De Mot, Rene" sort="De Mot, Rene" uniqKey="De Mot R" first="René" last="De Mot">René De Mot</name><affiliation wicri:level="1"><nlm:affiliation>Centre of Microbial and Plant Genetics, Faculty of Bioscience Engineering, University of Leuven, Heverlee, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Centre of Microbial and Plant Genetics, Faculty of Bioscience Engineering, University of Leuven, Heverlee</wicri:regionArea><wicri:noRegion>Heverlee</wicri:noRegion></affiliation></author><author><name sortKey="Donadio, Stefano" sort="Donadio, Stefano" uniqKey="Donadio S" first="Stefano" last="Donadio">Stefano Donadio</name><affiliation wicri:level="1"><nlm:affiliation>Naicons Srl, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Naicons Srl, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Donia, Mohamed S" sort="Donia, Mohamed S" uniqKey="Donia M" first="Mohamed S" last="Donia">Mohamed S. Donia</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Biology, Princeton University, Princeton, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region><settlement type="city">Princeton (New Jersey)</settlement></placeName><orgName type="university">Université de Princeton</orgName></affiliation></author><author><name sortKey="Van Der Donk, Wilfred A" sort="Van Der Donk, Wilfred A" uniqKey="Van Der Donk W" first="Wilfred A" last="Van Der Donk">Wilfred A. Van Der Donk</name><affiliation wicri:level="1"><nlm:affiliation>1] Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA. [2] Howard Hughes Medical Institute, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA. [2] Howard Hughes Medical Institute</wicri:regionArea><wicri:noRegion>USA. [2] Howard Hughes Medical Institute</wicri:noRegion></affiliation></author><author><name sortKey="Dorrestein, Pieter C" sort="Dorrestein, Pieter C" uniqKey="Dorrestein P" first="Pieter C" last="Dorrestein">Pieter C. Dorrestein</name><affiliation wicri:level="2"><nlm:affiliation>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA. [3] Collaborative Mass Spectrometry Innovation Center, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA. [3] Collaborative Mass Spectrometry Innovation Center, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Doyle, Sean" sort="Doyle, Sean" uniqKey="Doyle S" first="Sean" last="Doyle">Sean Doyle</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biology, Maynooth University, Maynooth, County Kildare, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Biology, Maynooth University, Maynooth, County Kildare</wicri:regionArea><orgName type="university">Université nationale d'Irlande à Maynooth</orgName><placeName><settlement type="city">Maynooth</settlement><region type="région" nuts="2">Leinster</region></placeName></affiliation></author><author><name sortKey="Driessen, Arnold J M" sort="Driessen, Arnold J M" uniqKey="Driessen A" first="Arnold J M" last="Driessen">Arnold J M. Driessen</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Ehling Schulz, Monika" sort="Ehling Schulz, Monika" uniqKey="Ehling Schulz M" first="Monika" last="Ehling-Schulz">Monika Ehling-Schulz</name><affiliation wicri:level="3"><nlm:affiliation>Functional Microbiology, Institute of Microbiology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Functional Microbiology, Institute of Microbiology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Entian, Karl Dieter" sort="Entian, Karl Dieter" uniqKey="Entian K" first="Karl-Dieter" last="Entian">Karl-Dieter Entian</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Fischbach, Michael A" sort="Fischbach, Michael A" uniqKey="Fischbach M" first="Michael A" last="Fischbach">Michael A. Fischbach</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gerwick, Lena" sort="Gerwick, Lena" uniqKey="Gerwick L" first="Lena" last="Gerwick">Lena Gerwick</name><affiliation wicri:level="2"><nlm:affiliation>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gerwick, William H" sort="Gerwick, William H" uniqKey="Gerwick W" first="William H" last="Gerwick">William H. Gerwick</name><affiliation wicri:level="2"><nlm:affiliation>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gross, Harald" sort="Gross, Harald" uniqKey="Gross H" first="Harald" last="Gross">Harald Gross</name><affiliation wicri:level="3"><nlm:affiliation>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Gust, Bertolt" sort="Gust, Bertolt" uniqKey="Gust B" first="Bertolt" last="Gust">Bertolt Gust</name><affiliation wicri:level="3"><nlm:affiliation>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Hertweck, Christian" sort="Hertweck, Christian" uniqKey="Hertweck C" first="Christian" last="Hertweck">Christian Hertweck</name><affiliation wicri:level="1"><nlm:affiliation>1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Friedrich Schiller University, Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Friedrich Schiller University, Jena</wicri:regionArea><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Hofte, Monica" sort="Hofte, Monica" uniqKey="Hofte M" first="Monica" last="Höfte">Monica Höfte</name><affiliation wicri:level="4"><nlm:affiliation>Department of Crop Protection, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Crop Protection, Faculty of Bioscience Engineering, Ghent University, Ghent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Jensen, Susan E" sort="Jensen, Susan E" uniqKey="Jensen S" first="Susan E" last="Jensen">Susan E. Jensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biological Sciences, University of Alberta, Edmonton, Alberta</wicri:regionArea><wicri:noRegion>Alberta</wicri:noRegion></affiliation></author><author><name sortKey="Ju, Jianhua" sort="Ju, Jianhua" uniqKey="Ju J" first="Jianhua" last="Ju">Jianhua Ju</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Katz, Leonard" sort="Katz, Leonard" uniqKey="Katz L" first="Leonard" last="Katz">Leonard Katz</name><affiliation wicri:level="2"><nlm:affiliation>Synthetic Biology Engineering Research Center (SynBERC), University of California Emeryville, Emeryville, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Synthetic Biology Engineering Research Center (SynBERC), University of California Emeryville, Emeryville, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Kaysser, Leonard" sort="Kaysser, Leonard" uniqKey="Kaysser L" first="Leonard" last="Kaysser">Leonard Kaysser</name><affiliation wicri:level="3"><nlm:affiliation>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Klassen, Jonathan L" sort="Klassen, Jonathan L" uniqKey="Klassen J" first="Jonathan L" last="Klassen">Jonathan L. Klassen</name><affiliation wicri:level="2"><nlm:affiliation>Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Keller, Nancy P" sort="Keller, Nancy P" uniqKey="Keller N" first="Nancy P" last="Keller">Nancy P. Keller</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA. [2] Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA. [2] Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Kormanec, Jan" sort="Kormanec, Jan" uniqKey="Kormanec J" first="Jan" last="Kormanec">Jan Kormanec</name><affiliation><nlm:affiliation>Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovak Republic.</nlm:affiliation><wicri:noCountry code="subField">Slovak Republic</wicri:noCountry></affiliation></author><author><name sortKey="Kuipers, Oscar P" sort="Kuipers, Oscar P" uniqKey="Kuipers O" first="Oscar P" last="Kuipers">Oscar P. Kuipers</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Kuzuyama, Tomohisa" sort="Kuzuyama, Tomohisa" uniqKey="Kuzuyama T" first="Tomohisa" last="Kuzuyama">Tomohisa Kuzuyama</name><affiliation wicri:level="4"><nlm:affiliation>Biotechnology Research Center, The University of Tokyo, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Biotechnology Research Center, The University of Tokyo, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Kyrpides, Nikos C" sort="Kyrpides, Nikos C" uniqKey="Kyrpides N" first="Nikos C" last="Kyrpides">Nikos C. Kyrpides</name><affiliation wicri:level="1"><nlm:affiliation>1] Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA. [2] Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>1] Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA. [2] Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah</wicri:regionArea><wicri:noRegion>Jeddah</wicri:noRegion></affiliation></author><author><name sortKey="Kwon, Hyung Jin" sort="Kwon, Hyung Jin" uniqKey="Kwon H" first="Hyung-Jin" last="Kwon">Hyung-Jin Kwon</name><affiliation wicri:level="1"><nlm:affiliation>Division of Bioscience and Bioinformatics, Myongji University, Yongin-si, Gyeonggi-Do, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Bioscience and Bioinformatics, Myongji University, Yongin-si, Gyeonggi-Do</wicri:regionArea><wicri:noRegion>Gyeonggi-Do</wicri:noRegion></affiliation></author><author><name sortKey="Lautru, Sylvie" sort="Lautru, Sylvie" uniqKey="Lautru S" first="Sylvie" last="Lautru">Sylvie Lautru</name><affiliation wicri:level="4"><nlm:affiliation>Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay</wicri:regionArea><placeName><settlement type="city">Orsay</settlement><settlement type="city">Orsay</settlement></placeName><orgName type="university">Université Paris-Sud</orgName></affiliation></author><author><name sortKey="Lavigne, Rob" sort="Lavigne, Rob" uniqKey="Lavigne R" first="Rob" last="Lavigne">Rob Lavigne</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Gene Technology, KU Leuven, Heverlee</wicri:regionArea><wicri:noRegion>Heverlee</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Chia Y" sort="Lee, Chia Y" uniqKey="Lee C" first="Chia Y" last="Lee">Chia Y. Lee</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas</wicri:regionArea><placeName><region type="state">Arkansas</region></placeName></affiliation></author><author><name sortKey="Linquan, Bai" sort="Linquan, Bai" uniqKey="Linquan B" first="Bai" last="Linquan">Bai Linquan</name><affiliation wicri:level="1"><nlm:affiliation>1] State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China. [2] School of Life Sciences &Biotechnology, Shanghai Jiao Tong University, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>1] State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China. [2] School of Life Sciences &Biotechnology, Shanghai Jiao Tong University, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Xinyu" sort="Liu, Xinyu" uniqKey="Liu X" first="Xinyu" last="Liu">Xinyu Liu</name><affiliation wicri:level="4"><nlm:affiliation>Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Liu, Wen" sort="Liu, Wen" uniqKey="Liu W" first="Wen" last="Liu">Wen Liu</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Luzhetskyy, Andriy" sort="Luzhetskyy, Andriy" uniqKey="Luzhetskyy A" first="Andriy" last="Luzhetskyy">Andriy Luzhetskyy</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Mahmud, Taifo" sort="Mahmud, Taifo" uniqKey="Mahmud T" first="Taifo" last="Mahmud">Taifo Mahmud</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Mast, Yvonne" sort="Mast, Yvonne" uniqKey="Mast Y" first="Yvonne" last="Mast">Yvonne Mast</name><affiliation wicri:level="3"><nlm:affiliation>Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Mendez, Carmen" sort="Mendez, Carmen" uniqKey="Mendez C" first="Carmen" last="Méndez">Carmen Méndez</name><affiliation wicri:level="1"><nlm:affiliation>1] Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain. [2] Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>1] Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain. [2] Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Mets Ketel, Mikko" sort="Mets Ketel, Mikko" uniqKey="Mets Ketel M" first="Mikko" last="Mets Ketel">Mikko Mets Ketel</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Biochemistry, University of Turku, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region><settlement type="city">Turku</settlement></placeName><orgName type="university">Université de Turku</orgName></affiliation></author><author><name sortKey="Micklefield, Jason" sort="Micklefield, Jason" uniqKey="Micklefield J" first="Jason" last="Micklefield">Jason Micklefield</name><affiliation wicri:level="4"><nlm:affiliation>School of Chemistry, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Chemistry, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Mitchell, Douglas A" sort="Mitchell, Douglas A" uniqKey="Mitchell D" first="Douglas A" last="Mitchell">Douglas A. Mitchell</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Moore, Bradley S" sort="Moore, Bradley S" uniqKey="Moore B" first="Bradley S" last="Moore">Bradley S. Moore</name><affiliation wicri:level="2"><nlm:affiliation>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Moreira, Leonilde M" sort="Moreira, Leonilde M" uniqKey="Moreira L" first="Leonilde M" last="Moreira">Leonilde M. Moreira</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Muller, Rolf" sort="Muller, Rolf" uniqKey="Muller R" first="Rolf" last="Müller">Rolf Müller</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Neilan, Brett A" sort="Neilan, Brett A" uniqKey="Neilan B" first="Brett A" last="Neilan">Brett A. Neilan</name><affiliation wicri:level="1"><nlm:affiliation>School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Nett, Markus" sort="Nett, Markus" uniqKey="Nett M" first="Markus" last="Nett">Markus Nett</name><affiliation wicri:level="1"><nlm:affiliation>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena</wicri:regionArea><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Nielsen, Jens" sort="Nielsen, Jens" uniqKey="Nielsen J" first="Jens" last="Nielsen">Jens Nielsen</name><affiliation wicri:level="1"><nlm:affiliation>1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="O Gara, Fergal" sort="O Gara, Fergal" uniqKey="O Gara F" first="Fergal" last="O'Gara">Fergal O'Gara</name><affiliation wicri:level="1"><nlm:affiliation>1] BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland. [2] Curtin University, School of Biomedical Sciences, Perth, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>1] BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland. [2] Curtin University, School of Biomedical Sciences, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Oikawa, Hideaki" sort="Oikawa, Hideaki" uniqKey="Oikawa H" first="Hideaki" last="Oikawa">Hideaki Oikawa</name><affiliation wicri:level="1"><nlm:affiliation>Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo</wicri:regionArea><wicri:noRegion>Sapporo</wicri:noRegion></affiliation></author><author><name sortKey="Osbourn, Anne" sort="Osbourn, Anne" uniqKey="Osbourn A" first="Anne" last="Osbourn">Anne Osbourn</name><affiliation wicri:level="1"><nlm:affiliation>Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Osburne, Marcia S" sort="Osburne, Marcia S" uniqKey="Osburne M" first="Marcia S" last="Osburne">Marcia S. Osburne</name><affiliation wicri:level="2"><nlm:affiliation>Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Ostash, Bohdan" sort="Ostash, Bohdan" uniqKey="Ostash B" first="Bohdan" last="Ostash">Bohdan Ostash</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv, Ukraine.</nlm:affiliation><country xml:lang="fr">Ukraine</country><wicri:regionArea>Department of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv</wicri:regionArea><wicri:noRegion>Lviv</wicri:noRegion></affiliation></author><author><name sortKey="Payne, Shelley M" sort="Payne, Shelley M" uniqKey="Payne S" first="Shelley M" last="Payne">Shelley M. Payne</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Pernodet, Jean Luc" sort="Pernodet, Jean Luc" uniqKey="Pernodet J" first="Jean-Luc" last="Pernodet">Jean-Luc Pernodet</name><affiliation wicri:level="4"><nlm:affiliation>Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay</wicri:regionArea><placeName><settlement type="city">Orsay</settlement><settlement type="city">Orsay</settlement></placeName><orgName type="university">Université Paris-Sud</orgName></affiliation></author><author><name sortKey="Petricek, Miroslav" sort="Petricek, Miroslav" uniqKey="Petricek M" first="Miroslav" last="Petricek">Miroslav Petricek</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Microbiology, Academy of Sciences of the Czech Republic (ASCR), Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Institute of Microbiology, Academy of Sciences of the Czech Republic (ASCR), Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Piel, Jorn" sort="Piel, Jorn" uniqKey="Piel J" first="Jörn" last="Piel">Jörn Piel</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Ploux, Olivier" sort="Ploux, Olivier" uniqKey="Ploux O" first="Olivier" last="Ploux">Olivier Ploux</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Interdisciplinaire des Energies de Demain (LIED), UMR 8236 CNRS, Université Paris Diderot, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Interdisciplinaire des Energies de Demain (LIED), UMR 8236 CNRS, Université Paris Diderot, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Raaijmakers, Jos M" sort="Raaijmakers, Jos M" uniqKey="Raaijmakers J" first="Jos M" last="Raaijmakers">Jos M. Raaijmakers</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen</wicri:regionArea><wicri:noRegion>Wageningen</wicri:noRegion></affiliation></author><author><name sortKey="Salas, Jose A" sort="Salas, Jose A" uniqKey="Salas J" first="José A" last="Salas">José A. Salas</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Departamento de Biología Funcional, Universidad de Oviedo, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Schmitt, Esther K" sort="Schmitt, Esther K" uniqKey="Schmitt E" first="Esther K" last="Schmitt">Esther K. Schmitt</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Novartis Campus, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Novartis Campus, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Scott, Barry" sort="Scott, Barry" uniqKey="Scott B" first="Barry" last="Scott">Barry Scott</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Institute of Fundamental Sciences, Massey University, Palmerston North</wicri:regionArea><wicri:noRegion>Palmerston North</wicri:noRegion></affiliation></author><author><name sortKey="Seipke, Ryan F" sort="Seipke, Ryan F" uniqKey="Seipke R" first="Ryan F" last="Seipke">Ryan F. Seipke</name><affiliation wicri:level="4"><nlm:affiliation>Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="Shen, Ben" sort="Shen, Ben" uniqKey="Shen B" first="Ben" last="Shen">Ben Shen</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA. [2] Molecular Therapeutics and Natural Products Library Initiative, The Scripps Research Institute, Jupiter, Florida, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA. [2] Molecular Therapeutics and Natural Products Library Initiative, The Scripps Research Institute, Jupiter, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Sherman, David H" sort="Sherman, David H" uniqKey="Sherman D" first="David H" last="Sherman">David H. Sherman</name><affiliation wicri:level="2"><nlm:affiliation>1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Sivonen, Kaarina" sort="Sivonen, Kaarina" uniqKey="Sivonen K" first="Kaarina" last="Sivonen">Kaarina Sivonen</name><affiliation wicri:level="4"><nlm:affiliation>Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Smanski, Michael J" sort="Smanski, Michael J" uniqKey="Smanski M" first="Michael J" last="Smanski">Michael J. Smanski</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA. [2] BioTechnology Institute, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA. [2] BioTechnology Institute, University of Minnesota-Twin Cities, Saint Paul, Minnesota</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Sosio, Margherita" sort="Sosio, Margherita" uniqKey="Sosio M" first="Margherita" last="Sosio">Margherita Sosio</name><affiliation wicri:level="1"><nlm:affiliation>Naicons Srl, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Naicons Srl, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Stegmann, Evi" sort="Stegmann, Evi" uniqKey="Stegmann E" first="Evi" last="Stegmann">Evi Stegmann</name><affiliation wicri:level="3"><nlm:affiliation>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Sussmuth, Roderich D" sort="Sussmuth, Roderich D" uniqKey="Sussmuth R" first="Roderich D" last="Süssmuth">Roderich D. Süssmuth</name><affiliation wicri:level="4"><nlm:affiliation>Institut für Chemie, Technische Universität Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Chemie, Technische Universität Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement><settlement type="city">Berlin</settlement></placeName><orgName type="university">Université technique de Berlin</orgName></affiliation></author><author><name sortKey="Tahlan, Kapil" sort="Tahlan, Kapil" uniqKey="Tahlan K" first="Kapil" last="Tahlan">Kapil Tahlan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland</wicri:regionArea><wicri:noRegion>Newfoundland</wicri:noRegion></affiliation></author><author><name sortKey="Thomas, Christopher M" sort="Thomas, Christopher M" uniqKey="Thomas C" first="Christopher M" last="Thomas">Christopher M. Thomas</name><affiliation wicri:level="4"><nlm:affiliation>School of Biosciences, University of Birmingham, Birmingham, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Biosciences, University of Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region><settlement type="city">Birmingham</settlement></placeName><orgName type="university">Université de Birmingham</orgName></affiliation></author><author><name sortKey="Tang, Yi" sort="Tang, Yi" uniqKey="Tang Y" first="Yi" last="Tang">Yi Tang</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Truman, Andrew W" sort="Truman, Andrew W" uniqKey="Truman A" first="Andrew W" last="Truman">Andrew W. Truman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Viaud, Muriel" sort="Viaud, Muriel" uniqKey="Viaud M" first="Muriel" last="Viaud">Muriel Viaud</name><affiliation wicri:level="1"><nlm:affiliation>Unité BIOlogie et GEstion des Risques en agriculture (BIOGER), Institut National de la Recherche Agronomique (INRA), Grignon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Unité BIOlogie et GEstion des Risques en agriculture (BIOGER), Institut National de la Recherche Agronomique (INRA), Grignon</wicri:regionArea><wicri:noRegion>Grignon</wicri:noRegion><wicri:noRegion>Grignon</wicri:noRegion></affiliation></author><author><name sortKey="Walton, Jonathan D" sort="Walton, Jonathan D" uniqKey="Walton J" first="Jonathan D" last="Walton">Jonathan D. Walton</name><affiliation wicri:level="4"><nlm:affiliation>Department of Energy Great Lakes Bioenergy Research Center and Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Energy Great Lakes Bioenergy Research Center and Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region><settlement type="city">East Lansing</settlement></placeName><orgName type="university">Université d'État du Michigan</orgName></affiliation></author><author><name sortKey="Walsh, Christopher T" sort="Walsh, Christopher T" uniqKey="Walsh C" first="Christopher T" last="Walsh">Christopher T. Walsh</name><affiliation wicri:level="2"><nlm:affiliation>Chemistry, Engineering &Medicine for Human Health (ChEM-H) Institute, Stanford University, Stanford, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Chemistry, Engineering &Medicine for Human Health (ChEM-H) Institute, Stanford University, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Weber, Tilmann" sort="Weber, Tilmann" uniqKey="Weber T" first="Tilmann" last="Weber">Tilmann Weber</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm</wicri:regionArea><wicri:noRegion>Hørsholm</wicri:noRegion></affiliation></author><author><name sortKey="Van Wezel, Gilles P" sort="Van Wezel, Gilles P" uniqKey="Van Wezel G" first="Gilles P" last="Van Wezel">Gilles P. Van Wezel</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Molecular Biotechnology, Institute of Biology, Leiden University, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Wilkinson, Barrie" sort="Wilkinson, Barrie" uniqKey="Wilkinson B" first="Barrie" last="Wilkinson">Barrie Wilkinson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Willey, Joanne M" sort="Willey, Joanne M" uniqKey="Willey J" first="Joanne M" last="Willey">Joanne M. Willey</name><affiliation wicri:level="2"><nlm:affiliation>Hofstra North Shore-Long Island Jewish School of Medicine, Hempstead, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hofstra North Shore-Long Island Jewish School of Medicine, Hempstead, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Wohlleben, Wolfgang" sort="Wohlleben, Wolfgang" uniqKey="Wohlleben W" first="Wolfgang" last="Wohlleben">Wolfgang Wohlleben</name><affiliation wicri:level="3"><nlm:affiliation>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Wright, Gerard D" sort="Wright, Gerard D" uniqKey="Wright G" first="Gerard D" last="Wright">Gerard D. Wright</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Ziemert, Nadine" sort="Ziemert, Nadine" uniqKey="Ziemert N" first="Nadine" last="Ziemert">Nadine Ziemert</name><affiliation wicri:level="3"><nlm:affiliation>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Changsheng" sort="Zhang, Changsheng" uniqKey="Zhang C" first="Changsheng" last="Zhang">Changsheng Zhang</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Zotchev, Sergey B" sort="Zotchev, Sergey B" uniqKey="Zotchev S" first="Sergey B" last="Zotchev">Sergey B. Zotchev</name><affiliation wicri:level="3"><nlm:affiliation>Department of Biotechnology, Norwegian University of Science and Technology, Trondheim, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Biotechnology, Norwegian University of Science and Technology, Trondheim</wicri:regionArea><placeName><settlement type="city">Trondheim</settlement><region type="région" nuts="2">Trøndelag</region></placeName></affiliation></author><author><name sortKey="Breitling, Rainer" sort="Breitling, Rainer" uniqKey="Breitling R" first="Rainer" last="Breitling">Rainer Breitling</name><affiliation wicri:level="4"><nlm:affiliation>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Takano, Eriko" sort="Takano, Eriko" uniqKey="Takano E" first="Eriko" last="Takano">Eriko Takano</name><affiliation wicri:level="4"><nlm:affiliation>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Glockner, Frank Oliver" sort="Glockner, Frank Oliver" uniqKey="Glockner F" first="Frank Oliver" last="Glöckner">Frank Oliver Glöckner</name><affiliation wicri:level="3"><nlm:affiliation>1] Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany. [2] Jacobs University Bremen gGmbH, Bremen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany. [2] Jacobs University Bremen gGmbH, Bremen</wicri:regionArea><placeName><region type="land" nuts="3">Brême (Land)</region><settlement type="city">Brême</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26284661</idno><idno type="pmid">26284661</idno><idno type="doi">10.1038/nchembio.1890</idno><idno type="wicri:Area/PubMed/Corpus">002A02</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002A02</idno><idno type="wicri:Area/PubMed/Curation">002932</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002932</idno><idno type="wicri:Area/PubMed/Checkpoint">002932</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002932</idno><idno type="wicri:Area/Ncbi/Merge">002947</idno><idno type="wicri:Area/Ncbi/Curation">002947</idno><idno type="wicri:Area/Ncbi/Checkpoint">002947</idno><idno type="wicri:Area/Main/Merge">002B29</idno><idno type="wicri:Area/Main/Curation">002B29</idno><idno type="wicri:Area/Main/Exploration">002B29</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Minimum Information about a Biosynthetic Gene cluster.</title><author><name sortKey="Medema, Marnix H" sort="Medema, Marnix H" uniqKey="Medema M" first="Marnix H" last="Medema">Marnix H. Medema</name><affiliation wicri:level="3"><nlm:affiliation>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen</wicri:regionArea><placeName><region type="land" nuts="3">Brême (Land)</region><settlement type="city">Brême</settlement></placeName></affiliation></author><author><name sortKey="Kottmann, Renzo" sort="Kottmann, Renzo" uniqKey="Kottmann R" first="Renzo" last="Kottmann">Renzo Kottmann</name><affiliation wicri:level="3"><nlm:affiliation>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen</wicri:regionArea><placeName><region type="land" nuts="3">Brême (Land)</region><settlement type="city">Brême</settlement></placeName></affiliation></author><author><name sortKey="Yilmaz, Pelin" sort="Yilmaz, Pelin" uniqKey="Yilmaz P" first="Pelin" last="Yilmaz">Pelin Yilmaz</name><affiliation wicri:level="3"><nlm:affiliation>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen</wicri:regionArea><placeName><region type="land" nuts="3">Brême (Land)</region><settlement type="city">Brême</settlement></placeName></affiliation></author><author><name sortKey="Cummings, Matthew" sort="Cummings, Matthew" uniqKey="Cummings M" first="Matthew" last="Cummings">Matthew Cummings</name><affiliation wicri:level="4"><nlm:affiliation>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Biggins, John B" sort="Biggins, John B" uniqKey="Biggins J" first="John B" last="Biggins">John B. Biggins</name><affiliation wicri:level="2"><nlm:affiliation>Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Blin, Kai" sort="Blin, Kai" uniqKey="Blin K" first="Kai" last="Blin">Kai Blin</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm</wicri:regionArea><wicri:noRegion>Hørsholm</wicri:noRegion></affiliation></author><author><name sortKey="De Bruijn, Irene" sort="De Bruijn, Irene" uniqKey="De Bruijn I" first="Irene" last="De Bruijn">Irene De Bruijn</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen</wicri:regionArea><wicri:noRegion>Wageningen</wicri:noRegion></affiliation></author><author><name sortKey="Chooi, Yit Heng" sort="Chooi, Yit Heng" uniqKey="Chooi Y" first="Yit Heng" last="Chooi">Yit Heng Chooi</name><affiliation wicri:level="1"><nlm:affiliation>1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA. [3] School of Chemistry and Biochemistry, University of Western Australia, Perth, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA. [3] School of Chemistry and Biochemistry, University of Western Australia, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Claesen, Jan" sort="Claesen, Jan" uniqKey="Claesen J" first="Jan" last="Claesen">Jan Claesen</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Coates, R Cameron" sort="Coates, R Cameron" uniqKey="Coates R" first="R Cameron" last="Coates">R Cameron Coates</name><affiliation wicri:level="2"><nlm:affiliation>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Cruz Morales, Pablo" sort="Cruz Morales, Pablo" uniqKey="Cruz Morales P" first="Pablo" last="Cruz-Morales">Pablo Cruz-Morales</name><affiliation wicri:level="1"><nlm:affiliation>Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato, México.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Mexique</country><wicri:regionArea>Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato</wicri:regionArea><wicri:noRegion>Guanajuato</wicri:noRegion></affiliation></author><author><name sortKey="Duddela, Srikanth" sort="Duddela, Srikanth" uniqKey="Duddela S" first="Srikanth" last="Duddela">Srikanth Duddela</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Dusterhus, Stephanie" sort="Dusterhus, Stephanie" uniqKey="Dusterhus S" first="Stephanie" last="Düsterhus">Stephanie Düsterhus</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Edwards, Daniel J" sort="Edwards, Daniel J" uniqKey="Edwards D" first="Daniel J" last="Edwards">Daniel J. Edwards</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry and Biochemistry, California State University, Chico, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry and Biochemistry, California State University, Chico, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Fewer, David P" sort="Fewer, David P" uniqKey="Fewer D" first="David P" last="Fewer">David P. Fewer</name><affiliation wicri:level="4"><nlm:affiliation>Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Garg, Neha" sort="Garg, Neha" uniqKey="Garg N" first="Neha" last="Garg">Neha Garg</name><affiliation wicri:level="2"><nlm:affiliation>Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Geiger, Christoph" sort="Geiger, Christoph" uniqKey="Geiger C" first="Christoph" last="Geiger">Christoph Geiger</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Gomez Escribano, Juan Pablo" sort="Gomez Escribano, Juan Pablo" uniqKey="Gomez Escribano J" first="Juan Pablo" last="Gomez-Escribano">Juan Pablo Gomez-Escribano</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Greule, Anja" sort="Greule, Anja" uniqKey="Greule A" first="Anja" last="Greule">Anja Greule</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Hadjithomas, Michalis" sort="Hadjithomas, Michalis" uniqKey="Hadjithomas M" first="Michalis" last="Hadjithomas">Michalis Hadjithomas</name><affiliation wicri:level="2"><nlm:affiliation>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Haines, Anthony S" sort="Haines, Anthony S" uniqKey="Haines A" first="Anthony S" last="Haines">Anthony S. Haines</name><affiliation wicri:level="4"><nlm:affiliation>School of Biosciences, University of Birmingham, Birmingham, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Biosciences, University of Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region><settlement type="city">Birmingham</settlement></placeName><orgName type="university">Université de Birmingham</orgName></affiliation></author><author><name sortKey="Helfrich, Eric J N" sort="Helfrich, Eric J N" uniqKey="Helfrich E" first="Eric J N" last="Helfrich">Eric J N. Helfrich</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Hillwig, Matthew L" sort="Hillwig, Matthew L" uniqKey="Hillwig M" first="Matthew L" last="Hillwig">Matthew L. Hillwig</name><affiliation wicri:level="4"><nlm:affiliation>Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Ishida, Keishi" sort="Ishida, Keishi" uniqKey="Ishida K" first="Keishi" last="Ishida">Keishi Ishida</name><affiliation wicri:level="1"><nlm:affiliation>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena</wicri:regionArea><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Jones, Adam C" sort="Jones, Adam C" uniqKey="Jones A" first="Adam C" last="Jones">Adam C. Jones</name><affiliation wicri:level="2"><nlm:affiliation>Gordon and Betty Moore Foundation, Palo Alto, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Gordon and Betty Moore Foundation, Palo Alto, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Jones, Carla S" sort="Jones, Carla S" uniqKey="Jones C" first="Carla S" last="Jones">Carla S. Jones</name><affiliation wicri:level="2"><nlm:affiliation>Sustainable Studies Program, Roosevelt University Chicago, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Sustainable Studies Program, Roosevelt University Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Jungmann, Katrin" sort="Jungmann, Katrin" uniqKey="Jungmann K" first="Katrin" last="Jungmann">Katrin Jungmann</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Kegler, Carsten" sort="Kegler, Carsten" uniqKey="Kegler C" first="Carsten" last="Kegler">Carsten Kegler</name><affiliation wicri:level="4"><nlm:affiliation>Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement><settlement type="city">Francfort-sur-le-Main</settlement></placeName><orgName type="university">Université Johann Wolfgang Goethe de Francfort-sur-le-Main</orgName></affiliation></author><author><name sortKey="Kim, Hyun Uk" sort="Kim, Hyun Uk" uniqKey="Kim H" first="Hyun Uk" last="Kim">Hyun Uk Kim</name><affiliation wicri:level="1"><nlm:affiliation>1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] BioInformatics Research Center, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] BioInformatics Research Center, Korea Advanced Institute of Science and Technology, Daejeon</wicri:regionArea><wicri:noRegion>Daejeon</wicri:noRegion></affiliation></author><author><name sortKey="Kotter, Peter" sort="Kotter, Peter" uniqKey="Kotter P" first="Peter" last="Kötter">Peter Kötter</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Krug, Daniel" sort="Krug, Daniel" uniqKey="Krug D" first="Daniel" last="Krug">Daniel Krug</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Masschelein, Joleen" sort="Masschelein, Joleen" uniqKey="Masschelein J" first="Joleen" last="Masschelein">Joleen Masschelein</name><affiliation wicri:level="1"><nlm:affiliation>1] Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium. [2] Laboratory of Food Microbiology, KU Leuven, Heverlee, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>1] Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium. [2] Laboratory of Food Microbiology, KU Leuven, Heverlee</wicri:regionArea><wicri:noRegion>Heverlee</wicri:noRegion></affiliation></author><author><name sortKey="Melnik, Alexey V" sort="Melnik, Alexey V" uniqKey="Melnik A" first="Alexey V" last="Melnik">Alexey V. Melnik</name><affiliation wicri:level="2"><nlm:affiliation>Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Mantovani, Simone M" sort="Mantovani, Simone M" uniqKey="Mantovani S" first="Simone M" last="Mantovani">Simone M. Mantovani</name><affiliation wicri:level="2"><nlm:affiliation>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Monroe, Emily A" sort="Monroe, Emily A" uniqKey="Monroe E" first="Emily A" last="Monroe">Emily A. Monroe</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biology, William Paterson University, Wayne, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, William Paterson University, Wayne, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Moore, Marcus" sort="Moore, Marcus" uniqKey="Moore M" first="Marcus" last="Moore">Marcus Moore</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland</wicri:regionArea><wicri:noRegion>Newfoundland</wicri:noRegion></affiliation></author><author><name sortKey="Moss, Nathan" sort="Moss, Nathan" uniqKey="Moss N" first="Nathan" last="Moss">Nathan Moss</name><affiliation wicri:level="2"><nlm:affiliation>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Nutzmann, Hans Wilhelm" sort="Nutzmann, Hans Wilhelm" uniqKey="Nutzmann H" first="Hans-Wilhelm" last="Nützmann">Hans-Wilhelm Nützmann</name><affiliation wicri:level="1"><nlm:affiliation>Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Pan, Guohui" sort="Pan, Guohui" uniqKey="Pan G" first="Guohui" last="Pan">Guohui Pan</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, The Scripps Research Institute, Jupiter, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Pati, Amrita" sort="Pati, Amrita" uniqKey="Pati A" first="Amrita" last="Pati">Amrita Pati</name><affiliation wicri:level="2"><nlm:affiliation>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Petras, Daniel" sort="Petras, Daniel" uniqKey="Petras D" first="Daniel" last="Petras">Daniel Petras</name><affiliation wicri:level="4"><nlm:affiliation>Institut für Chemie, Technische Universität Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Chemie, Technische Universität Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement><settlement type="city">Berlin</settlement></placeName><orgName type="university">Université technique de Berlin</orgName></affiliation></author><author><name sortKey="Reen, F Jerry" sort="Reen, F Jerry" uniqKey="Reen F" first="F Jerry" last="Reen">F Jerry Reen</name><affiliation wicri:level="1"><nlm:affiliation>BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author><author><name sortKey="Rosconi, Federico" sort="Rosconi, Federico" uniqKey="Rosconi F" first="Federico" last="Rosconi">Federico Rosconi</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Bioquímica y Genómica Microbianas, IBCE, Montevideo, Uruguay.</nlm:affiliation><country xml:lang="fr">Uruguay</country><wicri:regionArea>Departamento de Bioquímica y Genómica Microbianas, IBCE, Montevideo</wicri:regionArea><wicri:noRegion>Montevideo</wicri:noRegion></affiliation></author><author><name sortKey="Rui, Zhe" sort="Rui, Zhe" uniqKey="Rui Z" first="Zhe" last="Rui">Zhe Rui</name><affiliation wicri:level="2"><nlm:affiliation>1] Energy Biosciences Institute, University of California Berkeley, Berkeley, California, USA. [2] Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Energy Biosciences Institute, University of California Berkeley, Berkeley, California, USA. [2] Department of Chemical and Biomolecular Engineering, University of California Berkeley, Berkeley, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Tian, Zhenhua" sort="Tian, Zhenhua" uniqKey="Tian Z" first="Zhenhua" last="Tian">Zhenhua Tian</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Tobias, Nicholas J" sort="Tobias, Nicholas J" uniqKey="Tobias N" first="Nicholas J" last="Tobias">Nicholas J. Tobias</name><affiliation wicri:level="4"><nlm:affiliation>Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement><settlement type="city">Francfort-sur-le-Main</settlement></placeName><orgName type="university">Université Johann Wolfgang Goethe de Francfort-sur-le-Main</orgName></affiliation></author><author><name sortKey="Tsunematsu, Yuta" sort="Tsunematsu, Yuta" uniqKey="Tsunematsu Y" first="Yuta" last="Tsunematsu">Yuta Tsunematsu</name><affiliation wicri:level="1"><nlm:affiliation>1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka</wicri:regionArea><wicri:noRegion>Shizuoka</wicri:noRegion></affiliation></author><author><name sortKey="Wiemann, Philipp" sort="Wiemann, Philipp" uniqKey="Wiemann P" first="Philipp" last="Wiemann">Philipp Wiemann</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Wyckoff, Elizabeth" sort="Wyckoff, Elizabeth" uniqKey="Wyckoff E" first="Elizabeth" last="Wyckoff">Elizabeth Wyckoff</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Yan, Xiaohui" sort="Yan, Xiaohui" uniqKey="Yan X" first="Xiaohui" last="Yan">Xiaohui Yan</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, The Scripps Research Institute, Jupiter, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Yim, Grace" sort="Yim, Grace" uniqKey="Yim G" first="Grace" last="Yim">Grace Yim</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Yu, Fengan" sort="Yu, Fengan" uniqKey="Yu F" first="Fengan" last="Yu">Fengan Yu</name><affiliation wicri:level="2"><nlm:affiliation>1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Xie, Yunchang" sort="Xie, Yunchang" uniqKey="Xie Y" first="Yunchang" last="Xie">Yunchang Xie</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Aigle, Bertrand" sort="Aigle, Bertrand" uniqKey="Aigle B" first="Bertrand" last="Aigle">Bertrand Aigle</name><affiliation wicri:level="3"><nlm:affiliation>Dynamique des Génomes et Adaptation Microbienne, Université de Lorraine and Institut National de la Recherche Agronomique (INRA), Unité Mixte de Recherche (UMR) 1128, Vandœuvre-lès-Nancy, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Dynamique des Génomes et Adaptation Microbienne, Université de Lorraine and Institut National de la Recherche Agronomique (INRA), Unité Mixte de Recherche (UMR) 1128, Vandœuvre-lès-Nancy</wicri:regionArea><placeName><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Lorraine (région)</region><settlement type="city">Vandœuvre-lès-Nancy</settlement><settlement type="city" wicri:auto="agglo">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Apel, Alexander K" sort="Apel, Alexander K" uniqKey="Apel A" first="Alexander K" last="Apel">Alexander K. Apel</name><affiliation wicri:level="3"><nlm:affiliation>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Balibar, Carl J" sort="Balibar, Carl J" uniqKey="Balibar C" first="Carl J" last="Balibar">Carl J. Balibar</name><affiliation wicri:level="2"><nlm:affiliation>Infectious Disease Research, Merck Research Laboratories, Kenilworth, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Infectious Disease Research, Merck Research Laboratories, Kenilworth, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Balskus, Emily P" sort="Balskus, Emily P" uniqKey="Balskus E" first="Emily P" last="Balskus">Emily P. Balskus</name><affiliation wicri:level="4"><nlm:affiliation>Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region><settlement type="city">Cambridge (Massachusetts)</settlement></placeName><orgName type="university">Université Harvard</orgName></affiliation></author><author><name sortKey="Barona G Mez, Francisco" sort="Barona G Mez, Francisco" uniqKey="Barona G Mez F" first="Francisco" last="Barona-G Mez">Francisco Barona-G Mez</name><affiliation wicri:level="1"><nlm:affiliation>Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato, México.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Mexique</country><wicri:regionArea>Evolution of Metabolic Diversity Laboratory, Unidad de Genómica Avanzada (Langebio), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN), Irapuato, Guanajuato</wicri:regionArea><wicri:noRegion>Guanajuato</wicri:noRegion></affiliation></author><author><name sortKey="Bechthold, Andreas" sort="Bechthold, Andreas" uniqKey="Bechthold A" first="Andreas" last="Bechthold">Andreas Bechthold</name><affiliation wicri:level="3"><nlm:affiliation>Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University of Freiburg, Freiburg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Bode, Helge B" sort="Bode, Helge B" uniqKey="Bode H" first="Helge B" last="Bode">Helge B. Bode</name><affiliation wicri:level="4"><nlm:affiliation>1] Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany. [2] Buchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt, Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Merck Stiftungsprofessur für Molekulare Biotechnologie, Goethe Universität Frankfurt, Fachbereich Biowissenschaften, Frankfurt, Germany. [2] Buchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt, Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement><settlement type="city">Francfort-sur-le-Main</settlement></placeName><orgName type="university">Université Johann Wolfgang Goethe de Francfort-sur-le-Main</orgName></affiliation></author><author><name sortKey="Borriss, Rainer" sort="Borriss, Rainer" uniqKey="Borriss R" first="Rainer" last="Borriss">Rainer Borriss</name><affiliation wicri:level="3"><nlm:affiliation>Fachbereich Phytomedizin, Albrecht Thaer Institut, Humboldt Universität Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Fachbereich Phytomedizin, Albrecht Thaer Institut, Humboldt Universität Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Brady, Sean F" sort="Brady, Sean F" uniqKey="Brady S" first="Sean F" last="Brady">Sean F. Brady</name><affiliation wicri:level="2"><nlm:affiliation>Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Brakhage, Axel A" sort="Brakhage, Axel A" uniqKey="Brakhage A" first="Axel A" last="Brakhage">Axel A. Brakhage</name><affiliation wicri:level="1"><nlm:affiliation>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena</wicri:regionArea><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Caffrey, Patrick" sort="Caffrey, Patrick" uniqKey="Caffrey P" first="Patrick" last="Caffrey">Patrick Caffrey</name><affiliation wicri:level="1"><nlm:affiliation>UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Yi Qiang" sort="Cheng, Yi Qiang" uniqKey="Cheng Y" first="Yi-Qiang" last="Cheng">Yi-Qiang Cheng</name><affiliation wicri:level="2"><nlm:affiliation>UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>UNT System College of Pharmacy, University of North Texas Health Science Center, Fort Worth, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Clardy, Jon" sort="Clardy, Jon" uniqKey="Clardy J" first="Jon" last="Clardy">Jon Clardy</name><affiliation wicri:level="2"><nlm:affiliation>Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Cox, Russell J" sort="Cox, Russell J" uniqKey="Cox R" first="Russell J" last="Cox">Russell J. Cox</name><affiliation wicri:level="1"><nlm:affiliation>1] Institut für Organische Chemie, Leibniz Universität Hannover, Hannover, Germany. [2] School of Chemistry, University of Bristol, Bristol, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>1] Institut für Organische Chemie, Leibniz Universität Hannover, Hannover, Germany. [2] School of Chemistry, University of Bristol, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="De Mot, Rene" sort="De Mot, Rene" uniqKey="De Mot R" first="René" last="De Mot">René De Mot</name><affiliation wicri:level="1"><nlm:affiliation>Centre of Microbial and Plant Genetics, Faculty of Bioscience Engineering, University of Leuven, Heverlee, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Centre of Microbial and Plant Genetics, Faculty of Bioscience Engineering, University of Leuven, Heverlee</wicri:regionArea><wicri:noRegion>Heverlee</wicri:noRegion></affiliation></author><author><name sortKey="Donadio, Stefano" sort="Donadio, Stefano" uniqKey="Donadio S" first="Stefano" last="Donadio">Stefano Donadio</name><affiliation wicri:level="1"><nlm:affiliation>Naicons Srl, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Naicons Srl, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Donia, Mohamed S" sort="Donia, Mohamed S" uniqKey="Donia M" first="Mohamed S" last="Donia">Mohamed S. Donia</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Biology, Princeton University, Princeton, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Biology, Princeton University, Princeton, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region><settlement type="city">Princeton (New Jersey)</settlement></placeName><orgName type="university">Université de Princeton</orgName></affiliation></author><author><name sortKey="Van Der Donk, Wilfred A" sort="Van Der Donk, Wilfred A" uniqKey="Van Der Donk W" first="Wilfred A" last="Van Der Donk">Wilfred A. Van Der Donk</name><affiliation wicri:level="1"><nlm:affiliation>1] Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA. [2] Howard Hughes Medical Institute, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA. [2] Howard Hughes Medical Institute</wicri:regionArea><wicri:noRegion>USA. [2] Howard Hughes Medical Institute</wicri:noRegion></affiliation></author><author><name sortKey="Dorrestein, Pieter C" sort="Dorrestein, Pieter C" uniqKey="Dorrestein P" first="Pieter C" last="Dorrestein">Pieter C. Dorrestein</name><affiliation wicri:level="2"><nlm:affiliation>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA. [3] Collaborative Mass Spectrometry Innovation Center, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA. [3] Collaborative Mass Spectrometry Innovation Center, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Doyle, Sean" sort="Doyle, Sean" uniqKey="Doyle S" first="Sean" last="Doyle">Sean Doyle</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biology, Maynooth University, Maynooth, County Kildare, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Biology, Maynooth University, Maynooth, County Kildare</wicri:regionArea><orgName type="university">Université nationale d'Irlande à Maynooth</orgName><placeName><settlement type="city">Maynooth</settlement><region type="région" nuts="2">Leinster</region></placeName></affiliation></author><author><name sortKey="Driessen, Arnold J M" sort="Driessen, Arnold J M" uniqKey="Driessen A" first="Arnold J M" last="Driessen">Arnold J M. Driessen</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Molecular Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute and Zernike Institute for Advanced Materials, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Ehling Schulz, Monika" sort="Ehling Schulz, Monika" uniqKey="Ehling Schulz M" first="Monika" last="Ehling-Schulz">Monika Ehling-Schulz</name><affiliation wicri:level="3"><nlm:affiliation>Functional Microbiology, Institute of Microbiology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Functional Microbiology, Institute of Microbiology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Entian, Karl Dieter" sort="Entian, Karl Dieter" uniqKey="Entian K" first="Karl-Dieter" last="Entian">Karl-Dieter Entian</name><affiliation wicri:level="3"><nlm:affiliation>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute for Molecular Biosciences, Goethe University, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Fischbach, Michael A" sort="Fischbach, Michael A" uniqKey="Fischbach M" first="Michael A" last="Fischbach">Michael A. Fischbach</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA. [2] California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gerwick, Lena" sort="Gerwick, Lena" uniqKey="Gerwick L" first="Lena" last="Gerwick">Lena Gerwick</name><affiliation wicri:level="2"><nlm:affiliation>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gerwick, William H" sort="Gerwick, William H" uniqKey="Gerwick W" first="William H" last="Gerwick">William H. Gerwick</name><affiliation wicri:level="2"><nlm:affiliation>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Gross, Harald" sort="Gross, Harald" uniqKey="Gross H" first="Harald" last="Gross">Harald Gross</name><affiliation wicri:level="3"><nlm:affiliation>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Gust, Bertolt" sort="Gust, Bertolt" uniqKey="Gust B" first="Bertolt" last="Gust">Bertolt Gust</name><affiliation wicri:level="3"><nlm:affiliation>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Hertweck, Christian" sort="Hertweck, Christian" uniqKey="Hertweck C" first="Christian" last="Hertweck">Christian Hertweck</name><affiliation wicri:level="1"><nlm:affiliation>1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Friedrich Schiller University, Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany. [2] Friedrich Schiller University, Jena</wicri:regionArea><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Hofte, Monica" sort="Hofte, Monica" uniqKey="Hofte M" first="Monica" last="Höfte">Monica Höfte</name><affiliation wicri:level="4"><nlm:affiliation>Department of Crop Protection, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Crop Protection, Faculty of Bioscience Engineering, Ghent University, Ghent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Jensen, Susan E" sort="Jensen, Susan E" uniqKey="Jensen S" first="Susan E" last="Jensen">Susan E. Jensen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biological Sciences, University of Alberta, Edmonton, Alberta</wicri:regionArea><wicri:noRegion>Alberta</wicri:noRegion></affiliation></author><author><name sortKey="Ju, Jianhua" sort="Ju, Jianhua" uniqKey="Ju J" first="Jianhua" last="Ju">Jianhua Ju</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Katz, Leonard" sort="Katz, Leonard" uniqKey="Katz L" first="Leonard" last="Katz">Leonard Katz</name><affiliation wicri:level="2"><nlm:affiliation>Synthetic Biology Engineering Research Center (SynBERC), University of California Emeryville, Emeryville, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Synthetic Biology Engineering Research Center (SynBERC), University of California Emeryville, Emeryville, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Kaysser, Leonard" sort="Kaysser, Leonard" uniqKey="Kaysser L" first="Leonard" last="Kaysser">Leonard Kaysser</name><affiliation wicri:level="3"><nlm:affiliation>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Pharmaceutical Institute, Department of Pharmaceutical Biology, University of Tübingen, Tübingen, Germany. [2] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Klassen, Jonathan L" sort="Klassen, Jonathan L" uniqKey="Klassen J" first="Jonathan L" last="Klassen">Jonathan L. Klassen</name><affiliation wicri:level="2"><nlm:affiliation>Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular and Cell Biology, University of Connecticut, Storrs, Connecticut</wicri:regionArea><placeName><region type="state">Connecticut</region></placeName></affiliation></author><author><name sortKey="Keller, Nancy P" sort="Keller, Nancy P" uniqKey="Keller N" first="Nancy P" last="Keller">Nancy P. Keller</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA. [2] Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA. [2] Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Kormanec, Jan" sort="Kormanec, Jan" uniqKey="Kormanec J" first="Jan" last="Kormanec">Jan Kormanec</name><affiliation><nlm:affiliation>Institute of Molecular Biology, Slovak Academy of Sciences, Bratislava, Slovak Republic.</nlm:affiliation><wicri:noCountry code="subField">Slovak Republic</wicri:noCountry></affiliation></author><author><name sortKey="Kuipers, Oscar P" sort="Kuipers, Oscar P" uniqKey="Kuipers O" first="Oscar P" last="Kuipers">Oscar P. Kuipers</name><affiliation wicri:level="4"><nlm:affiliation>Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen</wicri:regionArea><placeName><settlement type="city">Groningue</settlement><region nuts="2" type="province">Groningue (province)</region><settlement type="city">Groningue (ville)</settlement></placeName><orgName type="university">Université de Groningue</orgName></affiliation></author><author><name sortKey="Kuzuyama, Tomohisa" sort="Kuzuyama, Tomohisa" uniqKey="Kuzuyama T" first="Tomohisa" last="Kuzuyama">Tomohisa Kuzuyama</name><affiliation wicri:level="4"><nlm:affiliation>Biotechnology Research Center, The University of Tokyo, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Biotechnology Research Center, The University of Tokyo, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Kyrpides, Nikos C" sort="Kyrpides, Nikos C" uniqKey="Kyrpides N" first="Nikos C" last="Kyrpides">Nikos C. Kyrpides</name><affiliation wicri:level="1"><nlm:affiliation>1] Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA. [2] Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.</nlm:affiliation><country xml:lang="fr">Arabie saoudite</country><wicri:regionArea>1] Department of Energy (DOE) Joint Genome Institute, Walnut Creek, California, USA. [2] Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah</wicri:regionArea><wicri:noRegion>Jeddah</wicri:noRegion></affiliation></author><author><name sortKey="Kwon, Hyung Jin" sort="Kwon, Hyung Jin" uniqKey="Kwon H" first="Hyung-Jin" last="Kwon">Hyung-Jin Kwon</name><affiliation wicri:level="1"><nlm:affiliation>Division of Bioscience and Bioinformatics, Myongji University, Yongin-si, Gyeonggi-Do, South Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Division of Bioscience and Bioinformatics, Myongji University, Yongin-si, Gyeonggi-Do</wicri:regionArea><wicri:noRegion>Gyeonggi-Do</wicri:noRegion></affiliation></author><author><name sortKey="Lautru, Sylvie" sort="Lautru, Sylvie" uniqKey="Lautru S" first="Sylvie" last="Lautru">Sylvie Lautru</name><affiliation wicri:level="4"><nlm:affiliation>Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay</wicri:regionArea><placeName><settlement type="city">Orsay</settlement><settlement type="city">Orsay</settlement></placeName><orgName type="university">Université Paris-Sud</orgName></affiliation></author><author><name sortKey="Lavigne, Rob" sort="Lavigne, Rob" uniqKey="Lavigne R" first="Rob" last="Lavigne">Rob Lavigne</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Gene Technology, KU Leuven, Heverlee, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Laboratory of Gene Technology, KU Leuven, Heverlee</wicri:regionArea><wicri:noRegion>Heverlee</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Chia Y" sort="Lee, Chia Y" uniqKey="Lee C" first="Chia Y" last="Lee">Chia Y. Lee</name><affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas</wicri:regionArea><placeName><region type="state">Arkansas</region></placeName></affiliation></author><author><name sortKey="Linquan, Bai" sort="Linquan, Bai" uniqKey="Linquan B" first="Bai" last="Linquan">Bai Linquan</name><affiliation wicri:level="1"><nlm:affiliation>1] State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China. [2] School of Life Sciences &Biotechnology, Shanghai Jiao Tong University, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>1] State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China. [2] School of Life Sciences &Biotechnology, Shanghai Jiao Tong University, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Xinyu" sort="Liu, Xinyu" uniqKey="Liu X" first="Xinyu" last="Liu">Xinyu Liu</name><affiliation wicri:level="4"><nlm:affiliation>Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Liu, Wen" sort="Liu, Wen" uniqKey="Liu W" first="Wen" last="Liu">Wen Liu</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Luzhetskyy, Andriy" sort="Luzhetskyy, Andriy" uniqKey="Luzhetskyy A" first="Andriy" last="Luzhetskyy">Andriy Luzhetskyy</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Mahmud, Taifo" sort="Mahmud, Taifo" uniqKey="Mahmud T" first="Taifo" last="Mahmud">Taifo Mahmud</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pharmaceutical Sciences, Oregon State University, Corvallis, Oregon</wicri:regionArea><placeName><region type="state">Oregon</region></placeName></affiliation></author><author><name sortKey="Mast, Yvonne" sort="Mast, Yvonne" uniqKey="Mast Y" first="Yvonne" last="Mast">Yvonne Mast</name><affiliation wicri:level="3"><nlm:affiliation>Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Mendez, Carmen" sort="Mendez, Carmen" uniqKey="Mendez C" first="Carmen" last="Méndez">Carmen Méndez</name><affiliation wicri:level="1"><nlm:affiliation>1] Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain. [2] Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>1] Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain. [2] Instituto Universitario de Oncología del Principado de Asturias (I.U.O.P.A), Universidad de Oviedo, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Mets Ketel, Mikko" sort="Mets Ketel, Mikko" uniqKey="Mets Ketel M" first="Mikko" last="Mets Ketel">Mikko Mets Ketel</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry, University of Turku, Turku, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Department of Biochemistry, University of Turku, Turku</wicri:regionArea><placeName><settlement type="city">Turku</settlement><region type="région" nuts="2">Finlande occidentale</region><settlement type="city">Turku</settlement></placeName><orgName type="university">Université de Turku</orgName></affiliation></author><author><name sortKey="Micklefield, Jason" sort="Micklefield, Jason" uniqKey="Micklefield J" first="Jason" last="Micklefield">Jason Micklefield</name><affiliation wicri:level="4"><nlm:affiliation>School of Chemistry, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Chemistry, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Mitchell, Douglas A" sort="Mitchell, Douglas A" uniqKey="Mitchell D" first="Douglas A" last="Mitchell">Douglas A. Mitchell</name><affiliation wicri:level="2"><nlm:affiliation>Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Moore, Bradley S" sort="Moore, Bradley S" uniqKey="Moore B" first="Bradley S" last="Moore">Bradley S. Moore</name><affiliation wicri:level="2"><nlm:affiliation>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. [2] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Moreira, Leonilde M" sort="Moreira, Leonilde M" uniqKey="Moreira L" first="Leonilde M" last="Moreira">Leonilde M. Moreira</name><affiliation wicri:level="1"><nlm:affiliation>Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.</nlm:affiliation><country xml:lang="fr">Portugal</country><wicri:regionArea>Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Lisboa</wicri:regionArea><wicri:noRegion>Lisboa</wicri:noRegion></affiliation></author><author><name sortKey="Muller, Rolf" sort="Muller, Rolf" uniqKey="Muller R" first="Rolf" last="Müller">Rolf Müller</name><affiliation wicri:level="3"><nlm:affiliation>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Helmholtz Institute for Pharmaceutical Research, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken</wicri:regionArea><placeName><region type="land" nuts="2">Sarre (Land)</region><settlement type="city">Sarrebruck</settlement></placeName></affiliation></author><author><name sortKey="Neilan, Brett A" sort="Neilan, Brett A" uniqKey="Neilan B" first="Brett A" last="Neilan">Brett A. Neilan</name><affiliation wicri:level="1"><nlm:affiliation>School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Nett, Markus" sort="Nett, Markus" uniqKey="Nett M" first="Markus" last="Nett">Markus Nett</name><affiliation wicri:level="1"><nlm:affiliation>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena</wicri:regionArea><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion><wicri:noRegion>Jena</wicri:noRegion></affiliation></author><author><name sortKey="Nielsen, Jens" sort="Nielsen, Jens" uniqKey="Nielsen J" first="Jens" last="Nielsen">Jens Nielsen</name><affiliation wicri:level="1"><nlm:affiliation>1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>1] Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark. [2] Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg</wicri:regionArea><wicri:noRegion>Gothenburg</wicri:noRegion></affiliation></author><author><name sortKey="O Gara, Fergal" sort="O Gara, Fergal" uniqKey="O Gara F" first="Fergal" last="O'Gara">Fergal O'Gara</name><affiliation wicri:level="1"><nlm:affiliation>1] BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland. [2] Curtin University, School of Biomedical Sciences, Perth, Western Australia, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>1] BIOMERIT Research Centre, School of Microbiology, University College Cork-National University of Ireland, Cork, Ireland. [2] Curtin University, School of Biomedical Sciences, Perth, Western Australia</wicri:regionArea><wicri:noRegion>Western Australia</wicri:noRegion></affiliation></author><author><name sortKey="Oikawa, Hideaki" sort="Oikawa, Hideaki" uniqKey="Oikawa H" first="Hideaki" last="Oikawa">Hideaki Oikawa</name><affiliation wicri:level="1"><nlm:affiliation>Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo</wicri:regionArea><wicri:noRegion>Sapporo</wicri:noRegion></affiliation></author><author><name sortKey="Osbourn, Anne" sort="Osbourn, Anne" uniqKey="Osbourn A" first="Anne" last="Osbourn">Anne Osbourn</name><affiliation wicri:level="1"><nlm:affiliation>Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Metabolic Biology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Osburne, Marcia S" sort="Osburne, Marcia S" uniqKey="Osburne M" first="Marcia S" last="Osburne">Marcia S. Osburne</name><affiliation wicri:level="2"><nlm:affiliation>Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Ostash, Bohdan" sort="Ostash, Bohdan" uniqKey="Ostash B" first="Bohdan" last="Ostash">Bohdan Ostash</name><affiliation wicri:level="1"><nlm:affiliation>Department of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv, Ukraine.</nlm:affiliation><country xml:lang="fr">Ukraine</country><wicri:regionArea>Department of Genetics and Biotechnology, Ivan Franko National University of Lviv, Lviv</wicri:regionArea><wicri:noRegion>Lviv</wicri:noRegion></affiliation></author><author><name sortKey="Payne, Shelley M" sort="Payne, Shelley M" uniqKey="Payne S" first="Shelley M" last="Payne">Shelley M. Payne</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Molecular Biosciences, The University of Texas, Austin, Texas, USA. [2] Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Pernodet, Jean Luc" sort="Pernodet, Jean Luc" uniqKey="Pernodet J" first="Jean-Luc" last="Pernodet">Jean-Luc Pernodet</name><affiliation wicri:level="4"><nlm:affiliation>Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institute of Integrative Biology of the Cell (I2BC), Commissariat à l'Energie Atomique (CEA), Centre National de la Recherche Scientifique (CNRS), Université Paris Sud, Orsay</wicri:regionArea><placeName><settlement type="city">Orsay</settlement><settlement type="city">Orsay</settlement></placeName><orgName type="university">Université Paris-Sud</orgName></affiliation></author><author><name sortKey="Petricek, Miroslav" sort="Petricek, Miroslav" uniqKey="Petricek M" first="Miroslav" last="Petricek">Miroslav Petricek</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Microbiology, Academy of Sciences of the Czech Republic (ASCR), Prague, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Institute of Microbiology, Academy of Sciences of the Czech Republic (ASCR), Prague</wicri:regionArea><placeName><settlement type="city">Prague</settlement><region type="région" nuts="2">Bohême centrale</region></placeName></affiliation></author><author><name sortKey="Piel, Jorn" sort="Piel, Jorn" uniqKey="Piel J" first="Jörn" last="Piel">Jörn Piel</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Microbiology, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich</wicri:regionArea><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Ploux, Olivier" sort="Ploux, Olivier" uniqKey="Ploux O" first="Olivier" last="Ploux">Olivier Ploux</name><affiliation wicri:level="3"><nlm:affiliation>Laboratoire Interdisciplinaire des Energies de Demain (LIED), UMR 8236 CNRS, Université Paris Diderot, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Laboratoire Interdisciplinaire des Energies de Demain (LIED), UMR 8236 CNRS, Université Paris Diderot, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Raaijmakers, Jos M" sort="Raaijmakers, Jos M" uniqKey="Raaijmakers J" first="Jos M" last="Raaijmakers">Jos M. Raaijmakers</name><affiliation wicri:level="1"><nlm:affiliation>Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Institute of Ecology (NIOO-KNAW), Department of Microbial Ecology, Wageningen</wicri:regionArea><wicri:noRegion>Wageningen</wicri:noRegion></affiliation></author><author><name sortKey="Salas, Jose A" sort="Salas, Jose A" uniqKey="Salas J" first="José A" last="Salas">José A. Salas</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Departamento de Biología Funcional, Universidad de Oviedo, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Schmitt, Esther K" sort="Schmitt, Esther K" uniqKey="Schmitt E" first="Esther K" last="Schmitt">Esther K. Schmitt</name><affiliation wicri:level="1"><nlm:affiliation>Novartis Institutes for BioMedical Research, Novartis Campus, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Novartis Institutes for BioMedical Research, Novartis Campus, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Scott, Barry" sort="Scott, Barry" uniqKey="Scott B" first="Barry" last="Scott">Barry Scott</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Institute of Fundamental Sciences, Massey University, Palmerston North</wicri:regionArea><wicri:noRegion>Palmerston North</wicri:noRegion></affiliation></author><author><name sortKey="Seipke, Ryan F" sort="Seipke, Ryan F" uniqKey="Seipke R" first="Ryan F" last="Seipke">Ryan F. Seipke</name><affiliation wicri:level="4"><nlm:affiliation>Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="Shen, Ben" sort="Shen, Ben" uniqKey="Shen B" first="Ben" last="Shen">Ben Shen</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA. [2] Molecular Therapeutics and Natural Products Library Initiative, The Scripps Research Institute, Jupiter, Florida, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Chemistry, The Scripps Research Institute, Jupiter, Florida, USA. [2] Molecular Therapeutics and Natural Products Library Initiative, The Scripps Research Institute, Jupiter, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Sherman, David H" sort="Sherman, David H" uniqKey="Sherman D" first="David H" last="Sherman">David H. Sherman</name><affiliation wicri:level="2"><nlm:affiliation>1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA. [4] Department of Microbiology &Immunology, University of Michigan, Ann Arbor, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Sivonen, Kaarina" sort="Sivonen, Kaarina" uniqKey="Sivonen K" first="Kaarina" last="Sivonen">Kaarina Sivonen</name><affiliation wicri:level="4"><nlm:affiliation>Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, Helsinki</wicri:regionArea><orgName type="university">Université d'Helsinki</orgName><placeName><settlement type="city">Helsinki</settlement><region type="région" nuts="2">Uusimaa</region></placeName></affiliation></author><author><name sortKey="Smanski, Michael J" sort="Smanski, Michael J" uniqKey="Smanski M" first="Michael J" last="Smanski">Michael J. Smanski</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA. [2] BioTechnology Institute, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota-Twin Cities, Saint Paul, Minnesota, USA. [2] BioTechnology Institute, University of Minnesota-Twin Cities, Saint Paul, Minnesota</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Sosio, Margherita" sort="Sosio, Margherita" uniqKey="Sosio M" first="Margherita" last="Sosio">Margherita Sosio</name><affiliation wicri:level="1"><nlm:affiliation>Naicons Srl, Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Naicons Srl, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Stegmann, Evi" sort="Stegmann, Evi" uniqKey="Stegmann E" first="Evi" last="Stegmann">Evi Stegmann</name><affiliation wicri:level="3"><nlm:affiliation>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Sussmuth, Roderich D" sort="Sussmuth, Roderich D" uniqKey="Sussmuth R" first="Roderich D" last="Süssmuth">Roderich D. Süssmuth</name><affiliation wicri:level="4"><nlm:affiliation>Institut für Chemie, Technische Universität Berlin, Berlin, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institut für Chemie, Technische Universität Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement><settlement type="city">Berlin</settlement></placeName><orgName type="university">Université technique de Berlin</orgName></affiliation></author><author><name sortKey="Tahlan, Kapil" sort="Tahlan, Kapil" uniqKey="Tahlan K" first="Kapil" last="Tahlan">Kapil Tahlan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biology, Memorial University of Newfoundland, St. John's, Newfoundland</wicri:regionArea><wicri:noRegion>Newfoundland</wicri:noRegion></affiliation></author><author><name sortKey="Thomas, Christopher M" sort="Thomas, Christopher M" uniqKey="Thomas C" first="Christopher M" last="Thomas">Christopher M. Thomas</name><affiliation wicri:level="4"><nlm:affiliation>School of Biosciences, University of Birmingham, Birmingham, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Biosciences, University of Birmingham, Birmingham</wicri:regionArea><placeName><settlement type="city">Birmingham</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Midlands de l'Ouest</region><settlement type="city">Birmingham</settlement></placeName><orgName type="university">Université de Birmingham</orgName></affiliation></author><author><name sortKey="Tang, Yi" sort="Tang, Yi" uniqKey="Tang Y" first="Yi" last="Tang">Yi Tang</name><affiliation wicri:level="2"><nlm:affiliation>1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>1] Department of Chemical and Biomolecular Engineering, University of California Los Angeles, Los Angeles, California, USA. [2] Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Truman, Andrew W" sort="Truman, Andrew W" uniqKey="Truman A" first="Andrew W" last="Truman">Andrew W. Truman</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Viaud, Muriel" sort="Viaud, Muriel" uniqKey="Viaud M" first="Muriel" last="Viaud">Muriel Viaud</name><affiliation wicri:level="1"><nlm:affiliation>Unité BIOlogie et GEstion des Risques en agriculture (BIOGER), Institut National de la Recherche Agronomique (INRA), Grignon, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Unité BIOlogie et GEstion des Risques en agriculture (BIOGER), Institut National de la Recherche Agronomique (INRA), Grignon</wicri:regionArea><wicri:noRegion>Grignon</wicri:noRegion><wicri:noRegion>Grignon</wicri:noRegion></affiliation></author><author><name sortKey="Walton, Jonathan D" sort="Walton, Jonathan D" uniqKey="Walton J" first="Jonathan D" last="Walton">Jonathan D. Walton</name><affiliation wicri:level="4"><nlm:affiliation>Department of Energy Great Lakes Bioenergy Research Center and Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Energy Great Lakes Bioenergy Research Center and Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan</wicri:regionArea><placeName><region type="state">Michigan</region><settlement type="city">East Lansing</settlement></placeName><orgName type="university">Université d'État du Michigan</orgName></affiliation></author><author><name sortKey="Walsh, Christopher T" sort="Walsh, Christopher T" uniqKey="Walsh C" first="Christopher T" last="Walsh">Christopher T. Walsh</name><affiliation wicri:level="2"><nlm:affiliation>Chemistry, Engineering &Medicine for Human Health (ChEM-H) Institute, Stanford University, Stanford, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Chemistry, Engineering &Medicine for Human Health (ChEM-H) Institute, Stanford University, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Weber, Tilmann" sort="Weber, Tilmann" uniqKey="Weber T" first="Tilmann" last="Weber">Tilmann Weber</name><affiliation wicri:level="1"><nlm:affiliation>Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm</wicri:regionArea><wicri:noRegion>Hørsholm</wicri:noRegion></affiliation></author><author><name sortKey="Van Wezel, Gilles P" sort="Van Wezel, Gilles P" uniqKey="Van Wezel G" first="Gilles P" last="Van Wezel">Gilles P. Van Wezel</name><affiliation wicri:level="3"><nlm:affiliation>Molecular Biotechnology, Institute of Biology, Leiden University, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Molecular Biotechnology, Institute of Biology, Leiden University, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Wilkinson, Barrie" sort="Wilkinson, Barrie" uniqKey="Wilkinson B" first="Barrie" last="Wilkinson">Barrie Wilkinson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich</wicri:regionArea><wicri:noRegion>Norwich</wicri:noRegion></affiliation></author><author><name sortKey="Willey, Joanne M" sort="Willey, Joanne M" uniqKey="Willey J" first="Joanne M" last="Willey">Joanne M. Willey</name><affiliation wicri:level="2"><nlm:affiliation>Hofstra North Shore-Long Island Jewish School of Medicine, Hempstead, New York, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hofstra North Shore-Long Island Jewish School of Medicine, Hempstead, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Wohlleben, Wolfgang" sort="Wohlleben, Wolfgang" uniqKey="Wohlleben W" first="Wolfgang" last="Wohlleben">Wolfgang Wohlleben</name><affiliation wicri:level="3"><nlm:affiliation>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Wright, Gerard D" sort="Wright, Gerard D" uniqKey="Wright G" first="Gerard D" last="Wright">Gerard D. Wright</name><affiliation wicri:level="4"><nlm:affiliation>Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry and Biomedical Sciences, The M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario</wicri:regionArea><orgName type="university">Université McMaster</orgName><placeName><settlement type="city">Hamilton (Ontario)</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Ziemert, Nadine" sort="Ziemert, Nadine" uniqKey="Ziemert N" first="Nadine" last="Ziemert">Nadine Ziemert</name><affiliation wicri:level="3"><nlm:affiliation>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] German Centre for Infection Research (DZIF), Partner Site Tübingen, Tübingen, Germany. [2] Microbiology/Biotechnology, Interfaculty Institute of Microbiology and Infection Medicine, Faculty of Science, University of Tübingen, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Changsheng" sort="Zhang, Changsheng" uniqKey="Zhang C" first="Changsheng" last="Zhang">Changsheng Zhang</name><affiliation wicri:level="3"><nlm:affiliation>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, RNAM Center for Marine Microbiology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou</wicri:regionArea><placeName><settlement type="city">Jiangmen</settlement><region type="province">Guangdong</region></placeName></affiliation></author><author><name sortKey="Zotchev, Sergey B" sort="Zotchev, Sergey B" uniqKey="Zotchev S" first="Sergey B" last="Zotchev">Sergey B. Zotchev</name><affiliation wicri:level="3"><nlm:affiliation>Department of Biotechnology, Norwegian University of Science and Technology, Trondheim, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Biotechnology, Norwegian University of Science and Technology, Trondheim</wicri:regionArea><placeName><settlement type="city">Trondheim</settlement><region type="région" nuts="2">Trøndelag</region></placeName></affiliation></author><author><name sortKey="Breitling, Rainer" sort="Breitling, Rainer" uniqKey="Breitling R" first="Rainer" last="Breitling">Rainer Breitling</name><affiliation wicri:level="4"><nlm:affiliation>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Takano, Eriko" sort="Takano, Eriko" uniqKey="Takano E" first="Eriko" last="Takano">Eriko Takano</name><affiliation wicri:level="4"><nlm:affiliation>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester</wicri:regionArea><placeName><settlement type="city">Manchester</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Manchester</region><settlement type="city">Manchester</settlement></placeName><orgName type="university">Université de Manchester</orgName></affiliation></author><author><name sortKey="Glockner, Frank Oliver" sort="Glockner, Frank Oliver" uniqKey="Glockner F" first="Frank Oliver" last="Glöckner">Frank Oliver Glöckner</name><affiliation wicri:level="3"><nlm:affiliation>1] Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany. [2] Jacobs University Bremen gGmbH, Bremen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>1] Microbial Genomics and Bioinformatics Research Group, Max Planck Institute for Marine Microbiology, Bremen, Germany. [2] Jacobs University Bremen gGmbH, Bremen</wicri:regionArea><placeName><region type="land" nuts="3">Brême (Land)</region><settlement type="city">Brême</settlement></placeName></affiliation></author></analytic><series><title level="j">Nature chemical biology</title><idno type="eISSN">1552-4469</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alkaloids (biosynthesis)</term><term>Bacteria (genetics)</term><term>Bacteria (metabolism)</term><term>Computational Biology (standards)</term><term>Databases, Genetic</term><term>Fungi (genetics)</term><term>Fungi (metabolism)</term><term>Genetic Markers</term><term>International Cooperation</term><term>Metagenome</term><term>Multigene Family</term><term>Peptide Biosynthesis, Nucleic Acid-Independent</term><term>Peptides (metabolism)</term><term>Plants (genetics)</term><term>Plants (metabolism)</term><term>Polyketides (metabolism)</term><term>Polysaccharides (biosynthesis)</term><term>Protein Biosynthesis</term><term>Terminology as Topic</term><term>Terpenes (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Alcaloïdes (biosynthèse)</term><term>Bactéries (génétique)</term><term>Bactéries (métabolisme)</term><term>Bases de données génétiques</term><term>Biologie informatique (normes)</term><term>Biosynthèse des protéines</term><term>Biosynthèse non ribosomique des peptides</term><term>Champignons (génétique)</term><term>Champignons (métabolisme)</term><term>Coopération internationale</term><term>Famille multigénique</term><term>Marqueurs génétiques</term><term>Métagénome</term><term>Peptides (métabolisme)</term><term>Plantes (génétique)</term><term>Plantes (métabolisme)</term><term>Polycétides (métabolisme)</term><term>Polyosides (biosynthèse)</term><term>Terminologie comme sujet</term><term>Terpènes (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Alkaloids</term><term>Polysaccharides</term></keywords><keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>Alcaloïdes</term><term>Polyosides</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Bacteria</term><term>Fungi</term><term>Plants</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Bactéries</term><term>Champignons</term><term>Plantes</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Bacteria</term><term>Fungi</term><term>Peptides</term><term>Plants</term><term>Polyketides</term><term>Terpenes</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Bactéries</term><term>Champignons</term><term>Peptides</term><term>Plantes</term><term>Polycétides</term><term>Terpènes</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Biologie informatique</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Computational Biology</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Databases, Genetic</term><term>Genetic Markers</term><term>International Cooperation</term><term>Metagenome</term><term>Multigene Family</term><term>Peptide Biosynthesis, Nucleic Acid-Independent</term><term>Protein Biosynthesis</term><term>Terminology as Topic</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Bases de données génétiques</term><term>Biosynthèse des protéines</term><term>Biosynthèse non ribosomique des peptides</term><term>Coopération internationale</term><term>Famille multigénique</term><term>Marqueurs génétiques</term><term>Métagénome</term><term>Terminologie comme sujet</term></keywords></textClass></profileDesc></teiHeader></TEI><affiliations><list><country><li>Allemagne</li><li>Arabie saoudite</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>Corée du Sud</li><li>Danemark</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Irlande (pays)</li><li>Italie</li><li>Japon</li><li>Mexique</li><li>Norvège</li><li>Nouvelle-Zélande</li><li>Pays-Bas</li><li>Portugal</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>République tchèque</li><li>Suisse</li><li>Suède</li><li>Ukraine</li><li>Uruguay</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Arkansas</li><li>Bade-Wurtemberg</li><li>Berlin</li><li>Bohême centrale</li><li>Brême (Land)</li><li>Californie</li><li>Canton de Zurich</li><li>Connecticut</li><li>District de Darmstadt</li><li>District de Fribourg-en-Brisgau</li><li>District de Tübingen</li><li>Finlande occidentale</li><li>Floride</li><li>Grand Est</li><li>Grand Manchester</li><li>Groningue (province)</li><li>Guangdong</li><li>Hesse (Land)</li><li>Hollande-Méridionale</li><li>Illinois</li><li>Leinster</li><li>Lorraine (région)</li><li>Massachusetts</li><li>Michigan</li><li>Midlands de l'Ouest</li><li>Minnesota</li><li>New Jersey</li><li>Ontario</li><li>Oregon</li><li>Pennsylvanie</li><li>Province de Flandre-Orientale</li><li>Région de Kantō</li><li>Région flamande</li><li>Sarre (Land)</li><li>Texas</li><li>Trøndelag</li><li>Uusimaa</li><li>Vienne (Autriche)</li><li>Wisconsin</li><li>Yorkshire-et-Humber</li><li>État de New York</li><li>Île-de-France</li></region><settlement><li>Berlin</li><li>Birmingham</li><li>Brême</li><li>Cambridge (Massachusetts)</li><li>East Lansing</li><li>Francfort-sur-le-Main</li><li>Fribourg-en-Brisgau</li><li>Gand</li><li>Groningue</li><li>Groningue (ville)</li><li>Hamilton (Ontario)</li><li>Helsinki</li><li>Jiangmen</li><li>Leeds</li><li>Leyde</li><li>Manchester</li><li>Maynooth</li><li>Nancy</li><li>Orsay</li><li>Paris</li><li>Pittsburgh</li><li>Prague</li><li>Princeton (New Jersey)</li><li>Sarrebruck</li><li>Tokyo</li><li>Trondheim</li><li>Turku</li><li>Tübingen</li><li>Vandœuvre-lès-Nancy</li><li>Vienne (Autriche)</li><li>Zurich</li></settlement><orgName><li>Université Harvard</li><li>Université Johann Wolfgang Goethe de Francfort-sur-le-Main</li><li>Université McMaster</li><li>Université Paris-Sud</li><li>Université d'Helsinki</li><li>Université d'État du Michigan</li><li>Université de Birmingham</li><li>Université de Gand</li><li>Université de Groningue</li><li>Université de Leeds</li><li>Université de Manchester</li><li>Université de Pittsburgh</li><li>Université de Princeton</li><li>Université de Tokyo</li><li>Université de Turku</li><li>Université nationale d'Irlande à Maynooth</li><li>Université technique de Berlin</li></orgName></list><tree><noCountry><name sortKey="Kormanec, Jan" sort="Kormanec, Jan" uniqKey="Kormanec J" first="Jan" last="Kormanec">Jan Kormanec</name></noCountry><country name="Allemagne"><region name="Brême (Land)"><name sortKey="Medema, Marnix H" sort="Medema, Marnix H" uniqKey="Medema M" first="Marnix H" last="Medema">Marnix H. 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Zotchev</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002B29 | SxmlIndent | more
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|texte= Minimum Information about a Biosynthetic Gene cluster.
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